ArticleAnnals of medicine and surgery (2012)2022
Effects of Otago Exercise Program on serum Interleukin-6 level in older women.
Article in Annals of medicine and surgery (2012), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed, 9 citations in OpenAlex.
- Fall-Related Physical Function, Executive Function, and Myokine Responses in Older Women with Obesity Participating in a 16-Week Combined Aquatic Exercise Program: A Prospective Observational Study.Medicina (Kaunas, Lithuania) · 2026Observational
- Muscle-Tumor Crosstalk in Exercise Oncology: Exercise-Induced Myokines and Cancer Cachexia.Cancers · 2026Review
- Clinically Meaningful or Just Measurable? What Physiologic Outcomes Tell Us About Aging Interventions.Current geriatrics reports · 2025Article
- Unlocking the potential of exercise: harnessing myokines to delay musculoskeletal aging and improve cognitive health.Frontiers in physiology · 2024Review
- Improving Capacity of Older Adults with Locomotive Syndrome Stage 1 Living in Nursing Home: A Pilot Clinical Trial.Annals of geriatric medicine and research · 2022Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Otago Exercise Program (OEP) has been demonstrated to minimize the risk of falling in older adults by improving muscular strength and balance. Meanwhile, reduced IL-6 level serves as a biomarker of regular physical activity. Objective: Analyzing OEP effect on decreased IL-6 level in elderly women. Methods: This study used a randomized control trial design from October 2020 to May 2021. 26 participants were divided into a treatment group (13 participants) and a control group (13 participants). The treatment group received OEP for 8 weeks, in which the OEP was carried out 3 times during the first week. On the other hand, the control group did not get intervention. The IL-6 level was measured 2 times, before and after OEP. The measurement results were analyzed using paired Results: The participants' average IL-6 level at pretest and posttest was 4.77 ± 1.71 pg/mL and 4.57 ± 1.74 pg/mL, respectively. The IL-16 level of the treatment group at pretest and posttest was 4.22 ± 1.72 pg/mL and 3.97 ± 1.67 pg/mL, respectively ( Conclusion: The OEP didn't lower serum IL-6 levels after eight weeks.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.