Evidence map›Paper›PMID 35600164›Full record

ArticleJournal of oral microbiology2022

Global transcriptional response of oral squamous cell carcinoma cell lines to health-associated oral bacteria - an

Divyashri Baraniya, Kumaraswamy Naidu Chitrala, Nezar Noor Al-Hebshi

Open access · goldAbstract read
In one paragraph

Article in Journal of oral microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Microorganisms · 2026
    Article
  3. Article
  4. Article
  5. Frontiers in cellular and infection microbiology · 2025
    Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. The role of oral microbiota in cancer.Frontiers in microbiology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Divyashri BaraniyaOral Microbiome Research Laboratory, Maurice H. Kornberg School of Dentistry, Temple University, Philadelphia, USA.
Kumaraswamy Naidu ChitralaFels Cancer Institute for Personalized Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA.
Nezar Noor Al-HebshiOral Microbiome Research Laboratory, Maurice H. Kornberg School of Dentistry, Temple University, Philadelphia, USA.
Temple University · USTemple University Health System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: We have recently demonstrated that health-associated oral bacteria Aim: To explore the effect of these three species on global transcriptome of OSCC cell lines. Methods: Gene expression of cell lines CAL27, SCC4 and SCC25 cocultured with the test species was assessed with Clariom-S Human microarray. Results: The results differed by species and cell line. Overall, the transcriptional changes by Conclusion: These findings provide a new insight into the role of commensal oral bacteria in OSCC. Animal studies are required to further explore them.

Indexed as

bacteriacell linemicroarray analysisMouth neoplasmstranscriptome

Identifiers

PMID35600164
PMCPMC9116255
OpenAlexW4280634852

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.