Evidence map›Paper›PMID 35600140›Full record

ArticleCurrent opinion in biomedical engineering2022

Emerging and future use of intra-surgical volumetric X-ray imaging and adjuvant tools for decision support in breast-conserving surgery.

Samuel S Streeter, Brady Hunt, Keith D Paulsen, Brian W Pogue

Abstract read
In one paragraph

Article in Current opinion in biomedical engineering, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Samuel S StreeterThayer School of Engineering, Dartmouth College, 14 Engineering Drive, Hanover, NH 03755, USA.
Brady HuntThayer School of Engineering, Dartmouth College, 14 Engineering Drive, Hanover, NH 03755, USA.
Keith D PaulsenThayer School of Engineering, Dartmouth College, 14 Engineering Drive, Hanover, NH 03755, USA.
Brian W PogueThayer School of Engineering, Dartmouth College, 14 Engineering Drive, Hanover, NH 03755, USA.

Funding

Optical Scatter Imaging System for Surgical Specimen Margin Assessment during Breast Conserving SurgeryR01CA192803 · NCI · DARTMOUTH COLLEGE · PI PAULSEN, KEITH D., POGUE, BRIAN WILLIAM · 2015 to 2019
$2.7M
Breast-conserving surgery resection margin assessment using optical light active line scanningF31CA257340 · NCI · DARTMOUTH COLLEGE · PI STREETER, SAMUEL STEWART · 2021 to 2022
$68k
NCI NIH HHS F31 CA257340NCI NIH HHS R01 CA192803
6 · The paper itself

Abstract

Breast-conserving surgery requires that resection margins be cancer-free, but re-excision rates due to positive margins have remained near 20% for much of the last decade with high variability between surgical centers. Recent studies have demonstrated that volumetric X-ray imaging improves margin assessment over standard techniques, given the speed of image reconstruction and full three-dimensional sensing of all margins. Deep learning approaches for automated analysis of volumetric medical image data are gaining traction and could play an important role streamlining the clinical workflow for intra-surgical specimen imaging. X-ray imaging systems currently deployed in clinical studies suffer from poor tumor-to-fibroglandular tissue contrast, motivating the development of adjuvant tools that could potentially complement volumetric X-ray scanning and further improve the future of intra-surgical margin assessment by real-time augmented guidance for the surgeon.

Indexed as

Breast-conserving surgeryDeep learningMargin assessmentMicro-computed tomographyTomosynthesis

Identifiers

PMID35600140
PMCPMC9119412

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.