Evidence map›Paper›PMID 35599917›Full record

ArticleJournal of the International Society of Sports Nutrition2022

The ergogenic effect of acute carnosine and anserine supplementation: dosing, timing, and underlying mechanism.

Sarah de Jager, Laura Blancquaert, Thibaux Van der Stede, Eline Lievens, Siegrid De Baere, Siska Croubels, Ettore Gilardoni, Luca G Regazzoni, Giancarlo Aldini, Jan G Bourgois and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the International Society of Sports Nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Sarah de JagerDepartment of Movement and Sports Sciences, Ghent University, Ghent, Belgium.ORCID https://orcid.org/0000-0002-0447-6888
Laura BlancquaertDepartment of Movement and Sports Sciences, Ghent University, Ghent, Belgium.
Thibaux Van der StedeDepartment of Movement and Sports Sciences, Ghent University, Ghent, Belgium.
Eline LievensDepartment of Movement and Sports Sciences, Ghent University, Ghent, Belgium.
Siegrid De BaereDepartment of Pharmacology, Toxicology and Biochemistry, Ghent University, Merelbeke, Belgium.
Siska CroubelsDepartment of Pharmacology, Toxicology and Biochemistry, Ghent University, Merelbeke, Belgium.
Ettore GilardoniDepartment of Pharmaceutical Sciences, University of Milan, Milan, Italy.
Luca G RegazzoniDepartment of Pharmaceutical Sciences, University of Milan, Milan, Italy.
Giancarlo AldiniDepartment of Pharmaceutical Sciences, University of Milan, Milan, Italy.
Jan G BourgoisDepartment of Movement and Sports Sciences, Ghent University, Ghent, Belgium.ORCID https://orcid.org/0000-0001-8972-1573
Wim DeraveDepartment of Movement and Sports Sciences, Ghent University, Ghent, Belgium.
Ghent University · BEUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Recent studies suggest that acute-combined carnosine and anserine supplementation has the potential to improve the performance of certain cycling protocols. Yet, data on optimal dose, timing of ingestion, effective exercise range, and mode of action are lacking. Three studies were conducted to establish dosing and timing guidelines concerning carnosine and anserine intake and to unravel the mechanism underlying the ergogenic effects. Methods: First, a dose response study A was conducted in which 11 men randomly received placebo, 10, 20, or 30 mg.kg Results: Study A showed a 3% peak power (p = 0.0005; 95% CI = 0.07 to 0.27; ES = 0.91) and 4.5% peak torque (p = 0.0006; 95% CI = 0.12 to 0.50; ES = 0.87) improvement on RSA and MVC, with 30 mg.kg Conclusions: These studies reveal that acute ingestion of 30 mg.kg

Indexed as

CarnosinePerformance-Enhancing SubstancesAnserineDietary SupplementsHumansIsometric ContractionMaleAnserineCarnosinePerformance-Enhancing SubstancesanserineCarnosineergogenic supplementmuscle perfusionneuromuscular function

Identifiers

PMID35599917
PMCPMC9116398
OpenAlexW4221112620

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.