ReviewFrontiers in psychiatry2022
The Molecular Basis of Resilience: A Narrative Review.
Review in Frontiers in psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed.
- Cognitive biotypes identified through ECG-derived workload and behavioral accuracy.Scientific reports · 2026Article
- Association of Psychological Resilience With Health-Related Quality of Life in Patients Undergoing Hip Fracture Surgery.Journal of patient experience · 2026Article
- Bridging reward and resilience: the endocannabinoid system as a unifying mechanism in exercise-induced protection against major depressive disorder.Frontiers in psychiatry · 2026Review
- Associations between mental health indicators and genital immune biomarkers among recent survivors of forced sex: A case-control analysis.Psychoneuroendocrinology · 2026Article
- Biomarkers and Mechanisms of Cardiovascular Susceptibility and Resilience to Post-Traumatic Stress Disorder.Reviews in cardiovascular medicine · 2025Review
- From adaptation to exhaustion: defining exposure-related malnutrition as a bioenergetic phenotype of aging.Biogerontology · 2025Review
- Resilience and brain health in global populations.Nature medicine · 2025Review
- Longitudinal Associations Between Cultural Engagement and Mental and Social Well-Being: A Fixed-Effects Analysis of the English Longitudinal Study of Ageing.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025Article
- Stress tests and biomarkers of resilience: Proceedings of the second state of resilience science conference.Journal of the American Geriatrics Society · 2025Article
- Mourning for Silence: Bereavement and Tinnitus-A Perspective.Journal of clinical medicine · 2025Article
- Microbial orchestration of neuroimmune crosstalk: from homeostasis to disease.Frontiers in immunology · 2025Review
- Epigenetics of Chronic Stress: Mechanisms and Health Impacts.Current genomics · 2025Review
- Selection for Resilience in Livestock Production Systems.International journal of molecular sciences · 2024Review
- Stress and cardiovascular disease: an update.Nature reviews. Cardiology · 2024Review
- The role of resilience in the relationship between stress and alcohol.Neurobiology of stress · 2024Article
- Early life adversity impacts alterations in brain structure and food addiction in individuals with high BMI.Scientific reports · 2024Article
- Review
- Biomarkers of stress resilience: A review.Neuroscience applied · 2024Article
- A virtually supervised exercise program improved fitness and mental wellness in healthy and comorbidity older adult individuals during the COVID-19 pandemic.Frontiers in public health · 2024Article
- The Effect of Peer Relationships on Adolescent Loneliness: The Role of Psychological Resilience and the OXTR Gene.Psychology research and behavior management · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Resilience refers to the adaptability of a person - an ability to "bounce-back" from stressors. We question if resilience can be strengthened, potentially to decrease the risk of stress-related disorders. Unfortunately, the molecular origins of resilience are complicated and not yet well understood. In this review, we examine the various physiological biomarkers of resilience, including the associated genes, epigenetic changes, and protein biomarkers associated with resilient phenotypes. In addition to assessing biomarkers that may indicate higher levels of resilience, we also review at length the many biomarkers that confer lower levels of resilience and may lead to disorders of low resilience, such as anxiety and depression. This large and encompassing review may help to identify the possible therapeutic targets of resilience. Hopefully these studies will lead to a future where stress-related disorders can be prevented, rather than treated.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.