Evidence map›Paper›PMID 35599735›Full record

ArticleFrontiers in neurology2022

The Clinical and Polynucleotide Repeat Expansion Analysis of

Xiaorong Hou, Wanzhen Li, Pan Liu, Zhen Liu, Yanchun Yuan, Jie Ni, Lu Shen, Beisha Tang, Junling Wang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Localization of Potential Energy in Hydrogen Bonds of theInternational journal of molecular sciences · 2025
    Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Xiaorong HouDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, China.
Wanzhen LiDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, China.
Pan LiuDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, China.
Zhen LiuDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, China.
Yanchun YuanDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, China.
Jie NiDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, China.
Lu ShenDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, China.
Beisha TangDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, China.
Junling WangDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, China.
Xiangya Hospital Central South University · CNCentral South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Repeat expansions, including those in Methods: In this study, 736 ALS patients and several hundred healthy controls were recruited. Polymerase chain reaction (PCR) and repeat-primed PCR (RP-PCR) were performed to determine the repeat lengths in Results: GGGGCC repeats in Conclusions: Our results demonstrated that pathogenetic repeats in

Indexed as

amyotrophic lateral sclerosisATXN2C9orf72neurodegenerative diseasenucleotide repeat expansion

Identifiers

PMID35599735
PMCPMC9120572
OpenAlexW4229071031

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.