Evidence map›Paper›PMID 35599725›Full record

ArticleJAC-antimicrobial resistance2022

Antibiotic susceptibility patterns of viridans group streptococci isolates in the United States from 2010 to 2020.

Nidhi Singh, Linda Poggensee, Yanqin Huang, Charlesnika T Evans, Katie J Suda, Zackery P Bulman

Abstract read
In one paragraph

Article in JAC-antimicrobial resistance, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. The First Case ofMedicina (Kaunas, Lithuania) · 2024
    Pooled it
  2. Article
  3. Article
  4. Genomic identification and characterization of Streptococcus oralis group that causes intraamniotic infection.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Article
  5. Article
  6. A Septicemic Child due to a Novel Streptococcal Species,Case reports in infectious diseases · 2025
    Article
  7. High prevalence of antibiotic resistance ofJournal of oral microbiology · 2025
    Article
  8. Article
  9. Low penicillin susceptibility inMicrobiology spectrum · 2024
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Clinical isolates ofAntimicrobial agents and chemotherapy · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nidhi SinghDepartment of Pharmacy Practice, University of Illinois at Chicago College of Pharmacy, Chicago, IL, USA.
Linda PoggenseeCenter of Innovation for Complex Chronic Healthcare, Edward Hines Jr VA Hospital, Hines, IL, USA.
Yanqin HuangDepartment of Pharmacy Practice, University of Illinois at Chicago College of Pharmacy, Chicago, IL, USA.
Charlesnika T EvansCenter for Healthcare Studies and Department of Preventive Medicine Institute for Public Health and Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Katie J SudaCenter for Health Equity Research and Promotion, VA Pittsburgh Healthcare System, U.S. Department of Veterans Affairs, Pittsburgh, PA, USA.
Zackery P BulmanDepartment of Pharmacy Practice, University of Illinois at Chicago College of Pharmacy, Chicago, IL, USA.ORCID https://orcid.org/0000-0002-5396-911X

Funding

Institutional Career DevelopmentKL2TR002002 · NCATS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI PHILLIPS, SHANE A · 2016 to 2024
$6.8M
Improving Veteran Health by Increasing Dental Stewardship of Antibiotics and OpioidsI01HX002452 · VA · EDWARD HINES JR VA HOSPITAL · PI SUDA, KJ · 2018 to 2021
–
HSR&D Research Career Scientist AwardIK6HX003156 · VA · EDWARD HINES JR VA HOSPITAL · PI EVANS, CHARLESNIKA T · 2020 to 2025
–
HSRD VA I01 HX002452HSRD VA IK6 HX003156NCATS NIH HHS KL2 TR002002
6 · The paper itself

Abstract

Background: Viridans group streptococci (VGS) are typically part of the commensal flora but can also cause severe invasive diseases such as infective endocarditis. There are limited data available showing antibiotic susceptibility over time for VGS. Objectives: To evaluate antibiotic susceptibility trends in VGS over time. Methods: Results: A total of 14 981 VGS isolates were included of which 19.5%, 0.7% and 79.8% were Conclusions: Susceptibility rates for some clinically relevant antibiotics declined between 2010 and 2020. This worrisome trend highlights the need to improve antimicrobial stewardship efforts to limit unnecessary antibiotic use and preserve empirical treatment options.

Identifiers

PMID35599725
PMCPMC9117386

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.