Evidence map›Paper›PMID 35599338›Full record

ArticlePharmacology research & perspectives2022

Association of income and educational levels with adherence to direct oral anticoagulant therapy in patients with incident atrial fibrillation: A Finnish nationwide cohort study.

Konsta Teppo, Jussi Jaakkola, Fausto Biancari, Olli Halminen, Miika Linna, Jari Haukka, Jukka Putaala, Paula Tiili, Ossi Lehtonen, Mikko Niemi and 5 more

Abstract read
In one paragraph

Article in Pharmacology research & perspectives, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Guideline
  2. Guideline
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Sex differences in the initiation of antithrombotic therapy in patients with atrial fibrillation in Germany.Clinical research in cardiology : official journal of the German Cardiac Society · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Social drivers in atrial fibrillation occurrence, screening, treatment, and outcomes: systematic-narrative hybrid review.European heart journal supplements : journal of the European Society of Cardiology · 2024
    Article
  12. Review
  13. Article
  14. Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Konsta TeppoUniversity of Turku, Turku, Finland.ORCID 0000-0002-4460-0994
Jussi JaakkolaUniversity of Turku, Turku, Finland.
Fausto BiancariHeart and Lung Center, Helsinki University Hospital, Helsinki, Finland.
Olli HalminenDepartment of Industrial Engineering and Management, Aalto University, Espoo, Finland.
Miika LinnaAalto University, Espoo, Finland.
Jari HaukkaUniversity of Helsinki, Helsinki, Finland.
Jukka PutaalaNeurology, Helsinki University Hospital, and University of Helsinki, Helsinki, Finland.
Paula TiiliUniversity of Helsinki, Helsinki, Finland.
Ossi LehtonenAalto University, Espoo, Finland.
Mikko NiemiUniversity of Helsinki, Helsinki, Finland.
Pirjo MustonenHeart Center, Turku University Hospital, Turku, Finland.
Janne KinnunenNeurology, Helsinki University Hospital, and University of Helsinki, Helsinki, Finland.
Juha HartikainenUniversity of Eastern Finland, Kuopio, Finland.
K E Juhani AiraksinenUniversity of Turku, Turku, Finland.
Mika LehtoHeart and Lung Center, Helsinki University Hospital, Helsinki, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Low socioeconomic status has been associated with poor outcomes in patients with atrial fibrillation (AF). However, little is known about socioeconomic disparities in adherence to stroke prevention with direct oral anticoagulants (DOACs). We assessed the hypothesis that AF patients with higher income or educational levels have better adherence to DOACs in terms of treatment implementation and persistence. The used nationwide registry-based FinACAF cohort covers all patients with incident AF starting DOACs in Finland during 2011-2018. The implementation analyses included 74 222 (mean age 72.7 ± 10.5 years, 50.8% female) patients, and persistence analyses included 67 503 (mean age 75.3 ± 8.9 years, 53.6% female) patients with indication for permanent anticoagulation (CHA

Indexed as

Atrial FibrillationAdministration, OralAgedAged, 80 and overAnticoagulantsCohort StudiesFemaleFinlandHumansMaleMiddle AgedAnticoagulantsadherenceatrial fibrillationdirect oral anticoagulantseducational levelincomepersistencesocioeconomic status

Identifiers

PMID35599338
PMCPMC9124817

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.