Evidence map›Paper›PMID 35599270›Full record

ArticleMedical oncology (Northwood, London, England)2022

Olaparib for Chinese metastatic castration-resistant prostate cancer: A real-world study of efficacy and gene predictive analysis.

Baijun Dong, Bin Yang, Wei Chen, Xinxing Du, Liancheng Fan, Xudong Yao, Wei Xue

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Medical oncology (Northwood, London, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. 2023 Canadian Urological Association guideline: Genetic testing in prostate cancer.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Baijun Dong *Department of Urology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Bin Yang *Department of Urology, Tenth People's Hospital, Shanghai Tongji University, Shanghai, China.
Wei Chen *Department of Urology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Xinxing Du *Department of Urology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Liancheng Fan *Department of Urology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Xudong YaoDepartment of Urology, Tenth People's Hospital, Shanghai Tongji University, Shanghai, China. yaoxudong1967@163.com.
Wei XueDepartment of Urology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China. xuewei@renji.com.ORCID http://orcid.org/0000-0003-0124-9433
Renji Hospital · CNTongji University · CNWenzhou Medical University · CN

Funding

National Natural Science Foundation of China 81772742
6 · The paper itself

Abstract

To evaluate the real-world effectiveness and gene predictive analysis of olaparib in Chinese patients with metastatic castration-resistant prostate cancer (mCRPC), a multicenter, retrospective, real-world study was conducted by involving Chinese patients with mCRPC from December 2017 to June 2021. Homologous Recombination repair (HRR)gene mutation (HRRm) status was identified using targeted next-generation sequencing (NGS). The primary end point includes prostate-specific antigen (PSA) response rate (PSA

Indexed as

Prostatic Neoplasms, Castration-ResistantAgedChinaHumansMaleMiddle AgedPhthalazinesPiperazinesProstate-Specific AntigenRetrospective StudiesTreatment OutcomeolaparibPhthalazinesPiperazinesProstate-Specific AntigenBRCA2HRR mutationsmCRPCOlaparibPSAPSA-PFSVUS

Identifiers

PMID35599270
OpenAlexW4281289331

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.