Evidence map›Paper›PMID 35599248›Full record

ArticleAnnals of intensive care2022

Does the cytokine adsorber CytoSorb

Christina Scharf, Ferdinand Weinelt, Ines Schroeder, Michael Paal, Michael Weigand, Michael Zoller, Michael Irlbeck, Charlotte Kloft, Josef Briegel, Uwe Liebchen

Open access · goldAbstract read
In one paragraph

Article in Annals of intensive care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Antibiotics and Other Drugs Removal by the CytoSorbAntibiotics (Basel, Switzerland) · 2026
    Review
  6. Article
  7. Article
  8. Challenges in the use of the CytoSorbJournal of medical case reports · 2025
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. [Extracorporeal procedures in sepsis].Die Anaesthesiologie · 2024
    Review
  15. Article
  16. Review
  17. Article
  18. Haemoadsorption in infective endocarditis: a systematic review.Indian journal of thoracic and cardiovascular surgery · 2024
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Christina ScharfDepartment of Anesthesiology, University Hospital, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.
Ferdinand WeineltDepartment of Clinical Pharmacy and Biochemistry, Institute of Pharmacy, Freie Universität Berlin, Kelchstr. 31, 12169, Berlin, Germany.
Ines SchroederDepartment of Anesthesiology, University Hospital, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.
Michael PaalInstitute of Laboratory Medicine, University Hospital, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.
Michael WeigandInstitute of Laboratory Medicine, University Hospital, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.
Michael ZollerDepartment of Anesthesiology, University Hospital, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.
Michael IrlbeckDepartment of Anesthesiology, University Hospital, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.
Charlotte KloftDepartment of Clinical Pharmacy and Biochemistry, Institute of Pharmacy, Freie Universität Berlin, Kelchstr. 31, 12169, Berlin, Germany.
Josef BriegelDepartment of Anesthesiology, University Hospital, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.
Uwe LiebchenDepartment of Anesthesiology, University Hospital, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany. uwe.liebchen@med.uni-muenchen.de.ORCID http://orcid.org/0000-0002-4375-0923
LMU Klinikum · DEFreie Universität Berlin · DEUniversity of Potsdam · DE

Funding

Medizinischen Fakultät, Ludwig-Maximilians-Universität München FöFoLe No. 002
6 · The paper itself

Abstract

backgroundHemadsorption of cytokines is used in critically ill patients with sepsis or septic shock. Concerns have been raised that the cytokine adsorber CytoSorb

methodsCritically ill patients with sepsis or septic shock receiving continuous renal replacement therapy and CytoSorb

results20 CytoSorb

conclusionWe recommend the infusion of 500 mg vancomycin over 2 h during CytoSorb

Indexed as

AdsorptionCritically ill patientsCytoSorb®PharmacokineticsSepsisVancomycin

Identifiers

PMID35599248
PMCPMC9124739
OpenAlexW4281298887

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.