Evidence map›Paper›PMID 35599194›Full record

ArticleTherapie

Public perceptions of the association between drug effectiveness and drug novelty in France during the COVID-19 pandemic.

Émilien Schultz, Léo Mignot, Jeremy K Ward, Daniela Boaventura Bomfim, Christian Chabannon, Julien Mancini

Abstract read
In one paragraph

Article in Therapie. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Émilien SchultzUniversité Paris Cité, IRD, Ceped, 75006 Paris, France; SESSTIM, Sciences Économiques & Sociales de la Santé & Traitement de l'Information Médicale, CANBIOS team (équipe labellisée LIGUE 2019), Aix-Marseille Université, Inserm, IRD, 13009 Marseille, France. Electronic address: emilien.schultz@ird.fr.
Léo MignotUniversity of Bordeaux, CNRS, CED, UMR 5116, 33600 Pessac, France; Sciences Po Bordeaux, CNRS, CED, UMR 5116, 33600 Pessac, France.
Jeremy K WardCERMES3, Inserm, CNRS, EHESS, Université de Paris Cité, 94801 Villejuif, France; VITROME, Aix-Marseille University, IRD, AP-HM, SSA, 13005 Marseille, France.
Daniela Boaventura BomfimUniversity of Bordeaux, CNRS, CED, UMR 5116, 33600 Pessac, France; SIRIC BRIO, CHU de Bordeaux, Institut Bergonié, Université of Bordeaux, Inserm, CNRS, 33000 Bordeaux, France.
Christian ChabannonModule Biothérapies du Centre d'Investigations Cliniques en Biothérapies, Inserm CBT-1409, Aix-Marseille Université, Institut Paoli-Calmettes comprehensive cancer center, 13005 Marseille, France.
Julien ManciniSESSTIM, Sciences Économiques & Sociales de la Santé & Traitement de l'Information Médicale, CANBIOS team (équipe labellisée LIGUE 2019), Aix-Marseille Université, Inserm, IRD, 13009 Marseille, France; BioSTIC, AP-HM, Timone, 13005 Marseille, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesDuring the coronavirus disease 2019 (COVID-19) pandemic, public debates overtly addressed the promises of new innovative drugs. Many of these debates pitted those who advocated for the development of new drugs by pharmaceutical companies against those who favored the repositioning of existing drugs. Our study explored perceptions of the association between drug novelty and effectiveness as well as perceptions of the role of the pharmaceutical industry in drug development.

methodsData were collected in January 2021 from a quota sample of the French population aged 18-75years (n=1,000) during the second round of the "Health Literacy Survey 2019" (HLS

resultsWe tested the hypothesis that individuals with a high level of familiarity with the health care system and those with a high level of trust in institutions are more likely to agree that new drugs are more effective than old ones and that drug development should be driven by the pharmaceutical industry. A quarter (25%) of respondents agreed that new drugs are always more effective than old ones. Agreement with this statement was stronger among respondents with a high level of familiarity with the health care system (as measured by the navigational health literacy score, OR 3.34 [2.13-5.24]). Respondents with a low level of trust in pharmaceutical companies or politicians were two times less likely to agree that new drugs are always more effective than old ones (OR 0.63 [0.42-0.95] and OR 0.68 [0.49-0.94], respectively). A high level of trust in pharmaceutical companies was reported by 42% of respondents, and 43% agreed that drug development should be driven by the pharmaceutical industry.

conclusionOur study shows that the perceived effectiveness of innovative drugs is associated with familiarity with the health care system and trust in institutions.

Indexed as

COVID-19PandemicsDrug IndustryHumansPharmaceutical PreparationsPublic OpinionPharmaceutical PreparationsCOVID-19Drug innovationPublic attitudeSocial pharmacologySociology

Identifiers

PMID35599194
PMCPMC9077798

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.