Evidence map›Paper›PMID 35599100›Full record

ArticleBiomaterials advances2022

Glycoengineering human neural stem cells (hNSCs) for adhesion improvement using a novel thiol-modified N-acetylmannosamine (ManNAc) analog.

Jian Du, Xiao Liu, Kevin J Yarema, Xiaofeng Jia

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomaterials advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Cell Surface Engineering Tools for Programming Living Assemblies.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jian DuDepartment of Neurosurgery, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Xiao LiuDepartment of Neurosurgery, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Kevin J YaremaDepartment of Biomedical Engineering, The Johns Hopkins School of Medicine, Baltimore, MD 21205, USA; Translational Cell and Tissue Engineering Center, The Johns Hopkins School of Medicine, Baltimore, MD 21231, USA. Electronic address: kyarema1@jhu.edu.
Xiaofeng JiaDepartment of Neurosurgery, University of Maryland School of Medicine, Baltimore, MD 21201, USA; Department of Biomedical Engineering, The Johns Hopkins School of Medicine, Baltimore, MD 21205, USA; Department of Orthopedics, University of Maryland School of Medicine, Baltimore, MD 21201, USA; Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD 21201, USA; Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins School of Medicine, Baltimore, MD 21205, USA. Electronic address: xjia@som.umaryland.edu.
University of Maryland, Baltimore · USJohns Hopkins Medicine · US

Funding

Stem Cell Surface Modification to Promote Nerve RegenerationR01NS117102 · NINDS · UNIVERSITY OF MARYLAND BALTIMORE · PI Xiaofeng Jia · 2021 to 2026
$2.0M
Brain Recovery after Cardiac Arrest with Metabolic Glycoengineered Stem CellsR01NS110387 · NINDS · UNIVERSITY OF MARYLAND BALTIMORE · PI JIA, XIAOFENG · 2018 to 2022
$1.7M
Engineering a Carbohydrate-Biomaterial Interface for Control of Wnt Signaling andR01EB005692 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI YAREMA, KEVIN J · 2007 to 2010
$1.4M
NIBIB NIH HHS R01 EB005692NINDS NIH HHS R01 NS110387NINDS NIH HHS R01 NS117102
6 · The paper itself

Abstract

This study sets the stage for the therapeutic use of Ac

Indexed as

LamininNeural Stem CellsCollagenFibronectinsHexosaminesHumansSulfhydryl CompoundsCollagenFibronectinsHexosaminesLamininN-acetylmannosamineSulfhydryl CompoundsCell adhesionHuman neural stem cellsManNAc analogMetabolic glycoengineering

Identifiers

PMID35599100
PMCPMC9300770
OpenAlexW4205390955

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.