Evidence map›Paper›PMID 35598547›Full record

Trial reportComplementary therapies in clinical practice2022

Efficacy of add-on Ayurveda and Yoga intervention in health care workers of tertiary care hospital during COVID-19: Randomized controlled trial.

Vandna Sharma, Bharat Krushna Khuntia, Manish Soneja, Vitthal G Huddar, S Ramakrishnan, Payal Sharma, Shubhangi Rathore, Varun Valliappan, Mohit Wadhawan, Varun Chhabra and 5 more

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Complementary therapies in clinical practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Vandna SharmaCentre for Integrative Medicine and Research (CIMR), All India Institute of Medical Sciences (AIIMS), New Delhi, 110029, India. Electronic address: vandnasharma25@gmail.com.
Bharat Krushna KhuntiaCentre for Integrative Medicine and Research (CIMR), All India Institute of Medical Sciences (AIIMS), New Delhi, 110029, India. Electronic address: aurobharat@gmail.com.
Manish SonejaDepartment of Medicine, All India Institute of Medical Sciences (AIIMS), New Delhi, 110029, India. Electronic address: manishsoneja@gmail.com.
Vitthal G HuddarDepartment of Kayachikitsa (Internal Medicine), All India Institute of Ayurveda, New Delhi, 110076, India. Electronic address: dr.vghuddar@aiia.gov.in.
S RamakrishnanDepartment of Cardiology, All India Institute of Medical Sciences (AIIMS), New Delhi, 110029, India. Electronic address: ramaaiims@gmail.com.
Payal SharmaCentre for Integrative Medicine and Research (CIMR), All India Institute of Medical Sciences (AIIMS), New Delhi, 110029, India. Electronic address: payalsharma204@gmail.com.
Shubhangi RathoreCentre for Integrative Medicine and Research (CIMR), All India Institute of Medical Sciences (AIIMS), New Delhi, 110029, India. Electronic address: drshubhangi.rathore@gmail.com.
Varun ValliappanCentre for Integrative Medicine and Research (CIMR), All India Institute of Medical Sciences (AIIMS), New Delhi, 110029, India. Electronic address: drvarun30@gmail.com.
Mohit WadhawanCentre for Integrative Medicine and Research (CIMR), All India Institute of Medical Sciences (AIIMS), New Delhi, 110029, India. Electronic address: mohit.wadhawan@yahoo.com.
Varun ChhabraCentre for Integrative Medicine and Research (CIMR), All India Institute of Medical Sciences (AIIMS), New Delhi, 110029, India. Electronic address: varunchhabra0@gmail.com.
Aman AgarwalCentre for Integrative Medicine and Research (CIMR), All India Institute of Medical Sciences (AIIMS), New Delhi, 110029, India. Electronic address: amanstatistician01@gmail.com.
Mansingh JatCentre for Integrative Medicine and Research (CIMR), All India Institute of Medical Sciences (AIIMS), New Delhi, 110029, India. Electronic address: mansingh.aiims@gmail.com.
Arvind KumarDepartment of Medicine, All India Institute of Medical Sciences (AIIMS), New Delhi, 110029, India. Electronic address: linktoarvind@gmail.com.
Tanuja Manoj NesariDepartment of Dravyaguna (Materia Medica & Pharmacology), All India Institute of Ayurveda, New Delhi, 110076, India. Electronic address: tnesari@hotmail.com.
Gautam SharmaCentre for Integrative Medicine and Research (CIMR), All India Institute of Medical Sciences (AIIMS), New Delhi, 110029, India. Electronic address: drgautamsharma12@gmail.com.
All India Institute of Medical Sciences · INNational Institute of Ayurveda · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe present study aimed to evaluate the safety and prophylactic efficacy of add-on Comprehensive Ayurveda and mindfulness-based Yoga (CAY) regimen to standard care among HealthCare Workers (HCWs) against COVID-19. MATERIALS AND

methodsThis prospective single-blind (outcome assessor-blinded) RCT was conducted in tertiary care hospital in Delhi during July 2020-April 2021. HCWs of both sexes were randomized to add-on CAY intervention or control group. The primary outcomes were the incidence of confirmed COVID-19 positive cases and influenza-like illness events (ILI). Secondary outcomes were anxiety (GAD-7), depression (PHQ-9), and quality of life (SF-36) at the end of 12 weeks.

resultsThree hundred fifty-six participants (181 in intervention and 175 in the control group) were randomized. With the modified intention to treat approach, we analyzed 309 participants. The mean age for the intervention and control group was 39.3 ± 10.1 and 36.6 ± 10 years, respectively. Incidence of COVID-19 event was higher in control group compared to CAY group (16 of 164 [9.8%] vs. 11 of 145 [7.6%]; P = 0.50). The incidence of ILI events was also higher in the control group as compared to the CAY group (14 of 164 [8.5%] vs 9 of 145 [6.2%]). The health change domain of the SF-36 questionnaire showed statistically significant improvement in the CAY group as compared to the control group (P < 0.01).

conclusionIncidence of COVID-19 and ILI events was lower in the CAY group compared with the contr ol group, though the difference is not statistically significant.

Indexed as

COVID-19YogaAdultFemaleHealth PersonnelHumansMaleMiddle AgedProspective StudiesQuality of LifeSARS-CoV-2Single-Blind MethodTertiary Care CentersTreatment OutcomeAnxietyAyurvedaComplementary therapyCOVID-19RCTYoga

Identifiers

PMID35598547
PMCPMC9080705
OpenAlexW4229364324

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.