Evidence map›Paper›PMID 35598313›Full record

ArticleJournal of cardiovascular electrophysiology2022

Posterior wall isolation in persistent atrial fibrillation feasibility, safety, durability, and efficacy.

René Worck, Samuel K Sørensen, Arne Johannessen, Martin Ruwald, Martin Haugdal, Jim Hansen

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Journal of cardiovascular electrophysiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06296888 (Radiofrequency Balloon Catheter Ablation for Atrial Fibrillation), which is not on this map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06296888 naunknown statusnot on this map

Radiofrequency Balloon Catheter Ablation for Atrial Fibrillation: Durability of Pulmonary Vein Isolation and Clinical Outcome - The RABAAF Study

TypeinterventionalSponsorJim HansenRan2022 to 2024Enrolled45ConditionsAtrial FibrillationArmsRadiofrequency balloon catheter ablation
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. One-year outcomes of focal pulsed-field ablation for redo procedures in atrial fibrillation and atypical flutter.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2025
    Article
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Emerging Tools and Techniques for Catheter Ablation of Cardiac Arrhythmias: A 2024 Update.The Journal of innovations in cardiac rhythm management · 2024
    Article
  10. Focal pulsed field ablation and ultrahigh-density mapping - versatile tools for all atrial arrhythmias? Initial procedural experiences.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2024
    Article
  11. Pulsed field ablation in real-world atrial fibrillation patients: clinical recurrence, operator learning curve and re-do procedural findings.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2023
    Article
  12. Article
  13. Posterior wall isolation in persistent atrial fibrillation. Long-term outcomes of a repeat procedure strategy.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2023
    Article
  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

René WorckDepartment of Cardiology, Copenhagen University Hospital Gentofte, Hellerup, Denmark.ORCID 0000-0001-9501-6168
Samuel K SørensenDepartment of Cardiology, Copenhagen University Hospital Gentofte, Hellerup, Denmark.ORCID 0000-0001-8134-2245
Arne JohannessenDepartment of Cardiology, Copenhagen University Hospital Gentofte, Hellerup, Denmark.ORCID 0000-0003-0294-3750
Martin RuwaldDepartment of Cardiology, Copenhagen University Hospital Gentofte, Hellerup, Denmark.ORCID 0000-0002-1541-309X
Martin HaugdalDepartment of Cardiology, Copenhagen University Hospital Gentofte, Hellerup, Denmark.
Jim HansenDepartment of Cardiology, Copenhagen University Hospital Gentofte, Hellerup, Denmark.ORCID 0000-0001-6600-9006
Gentofte Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPosterior wall isolation (PWI) added to pulmonary vein isolation (PVI) is increasingly used despite limited evidence of clinical benefit. We investigated the feasibility, durability, and efficacy of index-procedure PVI + PWI radio frequency ablation (RFA) in patients with persistent atrial fibrillation (PeAF). METHODS AND

resultsTwenty-four patients with PeAF participated in the prospective PeAF-Box study and underwent RFA with wide area circumferential ablation, roof- and inferior lines to achieve PVI + PWI at index procedure. Follow-up included monitoring by an implantable cardiac monitor, esophagoscopy and mandated invasive lesion-reassessment at 6 months. PWI was achieved at minor procedural cost in all patients following PVI. In 33% of patients a median of three ablations in the narrow zone between the center of the posterior wall (PW) and the posterior right carina was pivotal for swift achievement of PWI. At the 6-month reassessment procedure 85% (95% confidence interval [CI]: 77%-92%) of pulmonary veins (PVs) and 46% (95% CI: 26%-67%) of PWs remained durably isolated. AF recurred in 25% and was associated with PV-reconnection (p = .02) but not PW-reconnection (p = .27). AF-burden was 0% (interquartile range [IQR]: 0%-0%) overall and after recurrence 1% (IQR: 0%-7%).

conclusionIndex procedure PVI + PWI for PeAF was feasible when recognizing that limited ablation in a PW center-to-right-carina zone was required in a subset of patients. Despite limited chronic PWI durability this strategy was followed by low AF-burden. A PVI + PWI strategy appears promising in ablation for PeAF.

Indexed as

Atrial FibrillationCatheter AblationHeart AtriaPulmonary VeinsFeasibility StudiesHumansProspective StudiesRecurrenceTreatment OutcomeAF burdencenter-right zone (of left atrial posterior wall)implanted continuous rhythm monitormandated invasive reassessmentpersistent atrial fibrillationposterior wall

Identifiers

PMID35598313
PMCPMC9543717
OpenAlexW4281256684

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.