Evidence map›Paper›PMID 35598197›Full record

ArticleClinical child and family psychology review2022

Transdiagnostic Clinical Staging for Childhood Mental Health: An Adjunctive Tool for Classifying Internalizing and Externalizing Syndromes that Emerge in Children Aged 5-11 Years.

Vilas Sawrikar, Angus Macbeth, Karri Gillespie-Smith, Megan Brown, Andy Lopez-Williams, Kelsie Boulton, Adam Guestella, Ian Hickie

Abstract read
In one paragraph

Article in Clinical child and family psychology review, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Child and adolescent psychiatry: challenges, solutions, opportunities, and future directions.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026
    Article
  4. Transdiagnostic Clinical Staging in Youth Mental Health: A primer for clinical practice.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Vilas SawrikarCentre of Applied Developmental Psychology, University of Edinburgh, Edinburgh, UK. vilas.sawrikar@ed.ac.uk.ORCID 0000-0001-8160-0232
Angus MacbethCentre of Applied Developmental Psychology, University of Edinburgh, Edinburgh, UK.
Karri Gillespie-SmithCentre of Applied Developmental Psychology, University of Edinburgh, Edinburgh, UK.
Megan BrownADHD & Autism Psychological Services and Advocacy, Utica, NY, USA.
Andy Lopez-WilliamsADHD & Autism Psychological Services and Advocacy, Utica, NY, USA.
Kelsie BoultonBrain and Mind Centre, University of Sydney, Sydney, Australia.
Adam GuestellaBrain and Mind Centre, University of Sydney, Sydney, Australia.
Ian HickieBrain and Mind Centre, University of Sydney, Sydney, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clinical staging is now recognized as a key tool for facilitating innovation in personalized and preventative mental health care. It places a strong emphasis on the salience of indicated prevention, early intervention, and secondary prevention of major mental disorders. By contrast to established models for major mood and psychotic syndromes that emerge after puberty, developments in clinical staging for childhood-onset disorders lags significantly behind. In this article, criteria for a transdiagnostic staging model for those internalizing and externalizing disorders that emerge in childhood is presented. This sits alongside three putative pathophysiological profiles (developmental, circadian, and anxious-arousal) that may underpin these common illness trajectories. Given available evidence, we argue that it is now timely to develop a transdiagnostic staging model for childhood-onset syndromes. It is further argued that a transdiagnostic staging model has the potential to capture more precisely the dimensional, fluctuating developmental patterns of illness progression of childhood psychopathology. Given potential improvements in modelling etiological processes, and delivering more personalized interventions, transdiagnostic clinical staging for childhood holds much promise for assisting to improve outcomes. We finish by presenting an agenda for research in developments of transdiagnostic clinical staging for childhood mental health.

Indexed as

Mental DisordersMental HealthAnxietyChildHumansPsychopathologySyndromeDevelopmental psychopathologyDimensional classificationExternalising problemsInternalising problemsTransdiagnostic mental health

Identifiers

PMID35598197
PMCPMC9427921

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.