Evidence map›Paper›PMID 35598196›Full record

ArticleCellular and molecular life sciences : CMLS2022

Mettl14 mediates the inflammatory response of macrophages in atherosclerosis through the NF-κB/IL-6 signaling pathway.

Yang Zheng, Yunqi Li, Xianwen Ran, Di Wang, Xianghui Zheng, Maomao Zhang, Bo Yu, Yong Sun, Jian Wu

Open access · hybridAbstract read
In one paragraph

Article in Cellular and molecular life sciences : CMLS, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 111 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
111citing papers in PubMed, 1 pooled it
16.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

111 citing papers in PubMed, 1 synthesis or guideline pooled it, 185 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. METTL3/YTHDC1 axis-mediated mMolecular medicine (Cambridge, Mass.) · 2026
    Article
  6. Review
  7. Review
  8. Article
  9. mInternational journal of molecular medicine · 2026
    Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. The role of IL-6 in atherosclerosis: a narrative review.Frontiers in cardiovascular medicine · 2026
    Review
  16. mFrontiers in cell and developmental biology · 2026
    Review
  17. mFrontiers in immunology · 2026
    Review
  18. Review
  19. Review
  20. Article

51 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Yang ZhengDepartment of Cardiology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Yunqi LiDepartment of Cardiology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Xianwen RanDepartment of Cardiology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Di WangDepartment of Cardiology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Xianghui ZhengDepartment of Cardiology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Maomao ZhangDepartment of Cardiology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Bo YuDepartment of Cardiology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Yong SunDepartment of Cardiology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China. ssunyyong@126.com.
Jian WuDepartment of Cardiology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China. wujian780805@163.com.ORCID http://orcid.org/0000-0002-1192-321X
Ministry of Education of the People's Republic of China · CN

Funding

HMU Marshal Initiative Funding HMUMIF-21021National Natural Science Foundation of China 81972143National Natural Science Foundation of China 82002376National Natural Science Foundation of China 82072030National Natural Science Foundation of China 82172537
6 · The paper itself

Abstract

The inflammatory response of macrophages has been reported to play a critical role in atherosclerosis. The inflammatory state of macrophages is modified by epigenetic reprogramming. m

Indexed as

AtherosclerosisMacrophagesMethyltransferasesNF-kappa BHumansInflammationInterleukin-6Myeloid Differentiation Factor 88Signal TransductionTHP-1 CellsInterleukin-6MethyltransferasesMETTL14 protein, humanMyeloid Differentiation Factor 88NF-kappa BAtherosclerosisInflammatory responsem6A modificationMacrophageMettl14

Identifiers

PMID35598196
PMCPMC9124663
OpenAlexW4281259453

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.