Evidence map›Paper›PMID 35598023›Full record

ArticleItalian journal of pediatrics2022

Clinical picture and long-term symptoms of SARS-CoV-2 infection in an Italian pediatric population.

Silvia Bloise, Sara Isoldi, Alessia Marcellino, Enrica De Luca, Anna Dilillo, Saverio Mallardo, Vanessa Martucci, Mariateresa Sanseviero, Emanuela Del Giudice, Donatella Iorfida and 12 more

Open access · goldAbstract read
In one paragraph

Article in Italian journal of pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 5 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 5 syntheses or guidelines pooled it, 32 citations in OpenAlex.

  1. Pooled it
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  12. Year 2022: exploring COVID-19 pandemic in children.Italian journal of pediatrics · 2023
    Review
  13. Considerations in Children and Adolescents Related to Coronavirus Disease 2019 (COVID-19).Physical medicine and rehabilitation clinics of North America · 2023
    Review
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 2 institutions in 1 country.

Silvia BloiseDipartimento Materno Infantile E Di Scienze Urologiche, Sapienza Università Di Roma, UOC Di Pediatria e NeonatologiaOspedale Santa Maria Goretti, Polo Pontino, Rome, Lazio, Italy. silvia.bloise1989@gmail.com.ORCID http://orcid.org/0000-0002-2853-8318
Sara IsoldiDipartimento Materno Infantile E Di Scienze Urologiche, Sapienza Università Di Roma, UOC Di Pediatria e NeonatologiaOspedale Santa Maria Goretti, Polo Pontino, Rome, Lazio, Italy.
Alessia MarcellinoDipartimento Materno Infantile E Di Scienze Urologiche, Sapienza Università Di Roma, UOC Di Pediatria e NeonatologiaOspedale Santa Maria Goretti, Polo Pontino, Rome, Lazio, Italy.
Enrica De LucaDipartimento Materno Infantile E Di Scienze Urologiche, Sapienza Università Di Roma, UOC Di Pediatria e NeonatologiaOspedale Santa Maria Goretti, Polo Pontino, Rome, Lazio, Italy.
Anna DililloDipartimento Materno Infantile E Di Scienze Urologiche, Sapienza Università Di Roma, UOC Di Pediatria e NeonatologiaOspedale Santa Maria Goretti, Polo Pontino, Rome, Lazio, Italy.
Saverio MallardoDipartimento Materno Infantile E Di Scienze Urologiche, Sapienza Università Di Roma, UOC Di Pediatria e NeonatologiaOspedale Santa Maria Goretti, Polo Pontino, Rome, Lazio, Italy.
Vanessa MartucciDipartimento Materno Infantile E Di Scienze Urologiche, Sapienza Università Di Roma, UOC Di Pediatria e NeonatologiaOspedale Santa Maria Goretti, Polo Pontino, Rome, Lazio, Italy.
Mariateresa SansevieroDipartimento Materno Infantile E Di Scienze Urologiche, Sapienza Università Di Roma, UOC Di Pediatria e NeonatologiaOspedale Santa Maria Goretti, Polo Pontino, Rome, Lazio, Italy.
Emanuela Del GiudiceDipartimento Materno Infantile E Di Scienze Urologiche, Sapienza Università Di Roma, UOC Di Pediatria e NeonatologiaOspedale Santa Maria Goretti, Polo Pontino, Rome, Lazio, Italy.
Donatella IorfidaDipartimento Materno Infantile E Di Scienze Urologiche, Sapienza Università Di Roma, UOC Di Pediatria e NeonatologiaOspedale Santa Maria Goretti, Polo Pontino, Rome, Lazio, Italy.
Rita LeoneDipartimento Materno Infantile E Di Scienze Urologiche, Sapienza Università Di Roma, UOC Di Pediatria e NeonatologiaOspedale Santa Maria Goretti, Polo Pontino, Rome, Lazio, Italy.
Alessia TestaDipartimento Materno Infantile E Di Scienze Urologiche, Sapienza Università Di Roma, UOC Di Pediatria e NeonatologiaOspedale Santa Maria Goretti, Polo Pontino, Rome, Lazio, Italy.
Beatrice FrasaccoDipartimento Materno Infantile E Di Scienze Urologiche, Sapienza Università Di Roma, UOC Di Pediatria e NeonatologiaOspedale Santa Maria Goretti, Polo Pontino, Rome, Lazio, Italy.
Pietro GizzoneDipartimento Materno Infantile E Di Scienze Urologiche, Sapienza Università Di Roma, UOC Di Pediatria e NeonatologiaOspedale Santa Maria Goretti, Polo Pontino, Rome, Lazio, Italy.
Claudia Proietti CiolliDipartimento Materno Infantile E Di Scienze Urologiche, Sapienza Università Di Roma, UOC Di Pediatria e NeonatologiaOspedale Santa Maria Goretti, Polo Pontino, Rome, Lazio, Italy.
Alessandro SinceriDipartimento Materno Infantile E Di Scienze Urologiche, Sapienza Università Di Roma, UOC Di Pediatria e NeonatologiaOspedale Santa Maria Goretti, Polo Pontino, Rome, Lazio, Italy.
Francesca ZulianiDipartimento Materno Infantile E Di Scienze Urologiche, Sapienza Università Di Roma, UOC Di Pediatria e NeonatologiaOspedale Santa Maria Goretti, Polo Pontino, Rome, Lazio, Italy.
Elena ZanardiDipartimento Materno Infantile E Di Scienze Urologiche, Sapienza Università Di Roma, UOC Di Pediatria e NeonatologiaOspedale Santa Maria Goretti, Polo Pontino, Rome, Lazio, Italy.
Anna GambarottoDipartimento Materno Infantile E Di Scienze Urologiche, Sapienza Università Di Roma, UOC Di Pediatria e NeonatologiaOspedale Santa Maria Goretti, Polo Pontino, Rome, Lazio, Italy.
Anna Lisa GrandinettiDirezione Sanitaria Azienda, Sanitaria Locale Di Latina, Latina, Lazio, Italy.
Flavia VentrigliaDipartimento Materno Infantile E Di Scienze Urologiche, Sapienza Università Di Roma, UOC Di Pediatria e NeonatologiaOspedale Santa Maria Goretti, Polo Pontino, Rome, Lazio, Italy.
Riccardo LubranoDipartimento Materno Infantile E Di Scienze Urologiche, Sapienza Università Di Roma, UOC Di Pediatria e NeonatologiaOspedale Santa Maria Goretti, Polo Pontino, Rome, Lazio, Italy.
Ospedale Santa Maria Goretti · ITASL Roma · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSARS-CoV-2 infection in the pediatric age group has a milder course than in adults, but in some cases even children may present with severe forms or develop long-term consequences. The aim of this study was to analyze the clinical features, long-term effects, lifestyle changes and psychological effects of SARS-CoV-2 infection in a pediatric sample of the Italian population.

methodsWe conducted a telephone survey among 3075 children infected with SARS-CoV-2 in the Latina Local Health Authority. Outcomes included: clinical features of infection, long-term symptoms, lifestyle changes and emotional symptoms during the illness. The information obtained was automatically linked to a spreadsheet and analyzed.

resultsOne thousand four hundred thirteen children agreed to participate in the study; the mean age was 112.8 ± 21.9 months. Children were infected mainly inside familial clusters (59.6%; n = 842); 99% (n = 1399) of children were asymptomatic or exhibited mild symptoms. 20% (n = 259) of children experienced long-term symptoms; risk factors were: older age, higher body mass index and longer duration of infection. Throughout the period of infection, children spent most of the time on devices like tv-video, social media and mobile phone for non-educational activities. 58.8% (n = 620) of parents expressed a negative opinion about distance learning. Finally, we observed that 49,6% (n = 532) of children experienced psychological symptoms during quarantine period.

conclusionDespite a lower susceptibility to COVID-19 in children, it is important to keep the focus high in children, both because of the possible long symptoms after infection and the impact on a children's mental and physical health due to pandemic. We believe that the return to school or other extracurricular activities are important to correct some of the risk factors for the long COVID syndrome, as obesity, and to limit the cultural damage generated by distance learning and psychological effects related to restrictive measures.

Indexed as

COVID-19AdultChildHumansPandemicsPost-Acute COVID-19 SyndromeQuarantineSARS-CoV-2ChildrenLong COVIDPsychological effectsRisk factors

Identifiers

PMID35598023
PMCPMC9123625
OpenAlexW4281250607

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.