Evidence map›Paper›PMID 35597843›Full record

ArticleEuropean journal of nutrition2022

Macronutrient quality index and cardiovascular disease risk in the Seguimiento Universidad de Navarra (SUN) cohort.

Paola Vanegas, Itziar Zazpe, Susana Santiago, Cesar I Fernandez-Lazaro, Víctor de la O, Miguel Ángel Martínez-González

Open access · hybridAbstract read
In one paragraph

Article in European journal of nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Paola VanegasSchool of Pharmacy and Nutrition, Department of Nutrition and Food Sciences and Physiology, University of Navarra, Campus Universitario, 31080, Pamplona, Spain.
Itziar ZazpeSchool of Pharmacy and Nutrition, Department of Nutrition and Food Sciences and Physiology, University of Navarra, Campus Universitario, 31080, Pamplona, Spain.ORCID http://orcid.org/0000-0002-8787-2981
Susana SantiagoSchool of Pharmacy and Nutrition, Department of Nutrition and Food Sciences and Physiology, University of Navarra, Campus Universitario, 31080, Pamplona, Spain.ORCID http://orcid.org/0000-0002-6820-2819
Cesar I Fernandez-LazaroSchool of Medicine, Department of Preventive Medicine and Public Health, University of Navarra, Campus Universitario, 31080, Pamplona, Spain.ORCID http://orcid.org/0000-0003-2366-2528
Víctor de la OSchool of Medicine, Department of Preventive Medicine and Public Health, University of Navarra, Campus Universitario, 31080, Pamplona, Spain.ORCID http://orcid.org/0000-0002-9916-275X
Miguel Ángel Martínez-GonzálezSchool of Medicine, Department of Preventive Medicine and Public Health, University of Navarra, Campus Universitario, 31080, Pamplona, Spain. mamartinez@unav.es.ORCID http://orcid.org/0000-0002-3917-9808
Instituto de Salud Carlos III · ESNavarre Institute of Health Research · ESHarvard University · USUniversidad de Navarra · ES

Funding

Centro de Investigación Biomédica en Red-Fisiopatología de la Obesidad y Nutrición P14/01764Centro de Investigación Biomédica en Red-Fisiopatología de la Obesidad y Nutrición PI10/02293Centro de Investigación Biomédica en Red-Fisiopatología de la Obesidad y Nutrición PI10/02658Centro de Investigación Biomédica en Red-Fisiopatología de la Obesidad y Nutrición PI13/00615Centro de Investigación Biomédica en Red-Fisiopatología de la Obesidad y Nutrición PI14/01668Centro de Investigación Biomédica en Red-Fisiopatología de la Obesidad y Nutrición PI14/01798Centro de Investigación Biomédica en Red-Fisiopatología de la Obesidad y Nutrición PI17/01795Centro de Investigación Biomédica en Red-Fisiopatología de la Obesidad y Nutrición PI20/00564 y G03/140Gobierno de Navarra 122/2014Gobierno de Navarra 41/2016Gobierno de Navarra 45/2011Instituto de Salud Carlos III RD 06/0045
6 · The paper itself

Abstract

purposeTo assess the association between a multi-dimensional Macronutrient Quality Index (MQI) and the risk of cardiovascular disease (CVD) in a Mediterranean cohort.

methodsProspective analyses among 18,418 participants (mean age 36 years, 60.8% women) of the Seguimiento Universidad de Navarra (SUN) cohort. Dietary intake information was obtained through a validated semi-quantitative food-frequency questionnaire (FFQ). The MQI (expressing high-quality macronutrient intake) was calculated based on three previously reported quality indices: the Carbohydrate Quality Index (CQI), the Fat Quality Index (FQI), and the Healthy Plate Protein source Quality Index (HPPQI). Adherence to the Mediterranean diet (MedDiet) and Provegetarian Diet was evaluated using the Trichopoulou index and the score proposed by Martínez-González, respectively. CVD was defined as new-onset stroke, myocardial infarction, or CVD death.

resultsAfter a median follow-up time of 14 years (211,744 person-years), 171 cases of CVD were identified. A significant inverse association was found between the MQI and CVD risk with multivariable-adjusted HR for the highest vs. the lowest quartile of 0.60 (95% IC, 0.38-0.96; P

conclusionIn this Mediterranean cohort, we found a significant inverse relationship between a multidimensional MQI (expressing high-quality macronutrient intake) and a lower risk of CVD.

Indexed as

Cardiovascular DiseasesDiet, MediterraneanAdultFemaleFollow-Up StudiesHumansIncidenceMaleNutrientsProspective StudiesSpainCohortCVDMacronutrient qualityMediterranean dietProvegetarian diet

Identifiers

PMID35597843
PMCPMC9464119
OpenAlexW4281251562

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.