Evidence map›Paper›PMID 35597557›Full record

ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2022

Association between HIV and Prevalent Hypertension and Diabetes Mellitus in South Africa: Analysis of a Nationally Representative Cross-Sectional Survey.

Itai M Magodoro, Samson Okello, Mongiwethu Dungeni, Alison C Castle, Shakespeare Mureyani, Goodarz Danaei

Open access · goldAbstract read
In one paragraph

Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
9.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
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  4. Observational
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  6. Low metformin concentrations in obese people with HIV treated with dolutegravir.African journal of primary health care & family medicine · 2025
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  10. Review
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  12. Prevalence and Determinants of Household Self-Reported Diabetes Mellitus in Gauteng, South Africa.International journal of environmental research and public health · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 5 countries.

Itai M MagodoroDepartment of Medicine, Groote Schuur Hospital, University of Cape Town, Observatory, 7925, South Africa; Department of Global Health and Population, Harvard T.H. Chan School of Public Health, 67 Huntingdon St, Boston, MA 02115, USA. Electronic address: itai.magodoro@uct.ac.za.
Samson OkelloDepartment of Global Health and Population, Harvard T.H. Chan School of Public Health, 67 Huntingdon St, Boston, MA 02115, USA; Department of Internal Medicine, Mbarara University of Science and Technology, 1410 University Road, Mbarara District, Uganda; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, 135 Dauer Dr, Chapel Hill, NC, 27599, USA.
Mongiwethu DungeniSchool of Medicine, Cavendish University Zambia, Alick Nkhata Rd, Lusaka, Zambia.
Alison C CastleAfrica Health Research Institute, 719 Umbilo Off Ramp, Durban, 4001, South Africa; Division of Infectious Diseases, Massachusetts General Hospital, 55 Fruit St, Boston, MA, 02114, USA.
Shakespeare MureyaniGweru District Hospital, 7th Street, Gweru, Zimbabwe.
Goodarz DanaeiDepartment of Global Health and Population, Harvard T.H. Chan School of Public Health, 67 Huntingdon St, Boston, MA 02115, USA.
Cavendish University Zambia · ZMGweru Provincial Hospital · ZWMassachusetts General Hospital · USUniversity of Cape Town · ZAUniversity of North Carolina at Chapel Hill · US

Funding

Partnership for Global Health Research Training Program (Renewal)-Supplement for OBSSR, NCI, NCI-AIDS and NIDCDD43TW010543 · FIC · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Wafaie W Fawzi, DAVIDSON HOWES HAMER · 2017 to 2026
$12.1M
PROGRAM FOR AIDS CLINICAL RESEARCH TRAINING (PACRT)T32AI007433 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI MARK J SIEDNER · 1992 to 2026
$11.4M
Polycyclic aromatic hydrocarbons exposure and dietary risk of Esophageal squamous cell carcinoma in UgandaK43TW010715 · FIC · MBARARA UNIVERSITY/SCIENCE/ TECHNOLOGY · PI OKELLO, SAMSON · 2017 to 2021
$456k
FIC NIH HHS D43 TW010543FIC NIH HHS K43 TW010715NIAID NIH HHS T32 AI007433
6 · The paper itself

Abstract

objectivesCardiovascular disease (CVD) burden is increasing among persons living with HIV (PLWH) in sub-Saharan Africa. It is unclear whether this reflects absolute increase in HIV-related CVD risk or unmasking by improved survival. Therefore, we examined whether HIV is associated with adverse cardiometabolic profiles among South African adults.

methodsWe analyzed a nationally representative dataset (n=6420), estimating the weighted prevalence of hypertension, diabetes, and 10-year predicted risk of incident fatal/nonfatal CVD (if aged ≥40 years). Associations between HIV and cardiometabolic indices were assessed using log-binomial regression models adjusted for sociodemographic factors.

resultsHIV population prevalence was 18.9%, with a median age of 36 years. Hypertension (44.2% vs 45.4%), diabetes (18.6% vs 20.4%), and overweight/obesity (body mass index ≥25 kg/m

conclusionsPLWH in South Africa have better cardiometabolic disease profiles than the general population, and social determinants, rather than HIV, may have a greater influence on cardiometabolic risk. Designating PLWH a CVD high-risk group in South Africa is likely unwarranted.

Indexed as

Cardiovascular DiseasesDiabetes MellitusHIV InfectionsHypertensionAdultCross-Sectional StudiesFemaleHumansPrevalenceRisk FactorsSouth AfricaCardiometabolic diseaseDiabetesHIVHypertensionObesitySouth Africa

Identifiers

PMID35597557
PMCPMC9337715
OpenAlexW4280651057

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.