ArticleBJOG : an international journal of obstetrics and gynaecology2022
Metabolically healthy and unhealthy obesity and risk of vasomotor symptoms in premenopausal women: cross-sectional and cohort studies.
Article in BJOG : an international journal of obstetrics and gynaecology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Body roundness index and a body shape index and their associations with menopausal symptoms: a comparative cross-sectional study.BMC women's health · 2026Article
- Insulin Levels Early in Perimenopause Inform Vasomotor Symptom Incidence Across the Menopausal Transition.The Journal of clinical endocrinology and metabolism · 2026Article
- Longitudinal patterns and group heterogeneity of depressive symptoms during menopausal transition in middle-aged Korean women.Epidemiology and psychiatric sciences · 2025Article
- Article
- Insulin levels early in perimenopause inform vasomotor symptom incidence across the menopausal transition.medRxiv : the preprint server for health sciences · 2025Article
- The Metabolic Syndrome, a Human Disease.International journal of molecular sciences · 2024Review
- Association between body fat and bone mineral density in Korean adults: a cohort study.Scientific reports · 2023Article
- Metabolically healthy and unhealthy obesity and risk of vasomotor symptoms in premenopausal women: cross-sectional and cohort studies.BJOG : an international journal of obstetrics and gynaecology · 2022Article
- High low-density lipoprotein cholesterol level is associated with an increased risk of incident early-onset vasomotor symptoms.Scientific reports · 2022Article
- Nonalcoholic Fatty Liver Disease and Risk of Early-Onset Vasomotor Symptoms in Lean and Overweight Premenopausal Women.Nutrients · 2022Article
- Alcohol Consumption Patterns and Risk of Early-Onset Vasomotor Symptoms in Premenopausal Women.Nutrients · 2022Article
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Authors and funding
16 authors.
Funding
Abstract
objectiveTo examine the relationship between metabolically healthy and unhealthy obesity phenotypes and risk of vasomotor symptoms (VMS) in premenopausal women.
designProspective cohort study.
settingMiddle-aged women in a cohort based on regular health screening examinations. POPULATION: Premenopausal Korean women aged 42-52 years were recruited and were followed up for a median of 4.2 years. The cross-sectional and cohort studies comprised 4672 women and 2590 women without VMS at baseline, respectively.
methodsAdiposity measures included body mass index (BMI), waist circumference and percentage body fat. Being metabolically healthy was defined as not having any metabolic syndrome components or a homeostasis model assessment of insulin resistance of 2.5 or more. MAIN OUTCOMES MEASURES: VMS (hot flushes and night sweats) assessed using the questionnaire.
resultsAll adiposity measures were positively associated with an increased risk of VMS in both cross-sectional and longitudinal studies. The multivariable-adjusted prevalence ratio (95% confidence interval [CI]) for VMS comparing percentage body fat of 35% or more with the reference was 1.47 (95% CI 1.14-1.90) in metabolically healthy women, and the corresponding prevalence ratio was 2.32 (95% CI 1.42-3.78) in metabolically unhealthy women (P
conclusionsMaintaining normal weight and being metabolically healthy may help to prevent VMS in premenopausal women. TWEETABLE ABSTRACT: Avoiding obesity and a metabolically unhealthy status may help reduce vasomotor symptoms in premenopausal women.
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