Evidence map›Paper›PMID 35596848›Full record

ArticleMaternal and child health journal2022

Poor sleep Quality and Obstructive Sleep Apnea are Associated with Maternal Mood, and Anxiety Disorders in Pregnancy.

Elia Rubio, Elizabeth J Levey, Marta B Rondon, Lauren Friedman, Sixto E Sanchez, Michelle A Williams, Bizu Gelaye

Open access · greenAbstract read
In one paragraph

Article in Maternal and child health journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Elia RubioDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Elizabeth J LeveyThe Chester M. Pierce, M.D. Division of Global Psychiatry, Massachusetts General Hospital, Boston, MA, USA.
Marta B RondonDepartment of Medicine, Universidad Peruana Cayetano Heredia, Lima, Peru.
Lauren FriedmanDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Sixto E SanchezAsociación Civil Proyectos en Salud (PROESA), Lima, Peru.
Michelle A WilliamsDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Bizu GelayeDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA. bgelaye@hsph.harvard.edu.ORCID http://orcid.org/0000-0001-7934-548X
Harvard University · USPeruvian University of Applied Sciences · PEUniversidad Peruana Cayetano Heredia · PE

Funding

University of Washington MHIRT Training Program GrantT37MD001449 · NIMHD · UNIVERSITY OF WASHINGTON · PI WILLIAMS, MICHELLE A. · 2005 to 2018
$3.5M
A Cohort Study of Preterm Delivery in Relation to Partner Abuse, Mood and AnxietyR01HD059835 · NICHD · UNIVERSITY OF WASHINGTON · PI WILLIAMS, MICHELLE A. · 2010 to 2014
$2.8M
Adaptation and assessment of a family intervention designed to improve maternal and child mental health in resource-limited settingsK23MH115169 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI LEVEY, ELIZABETH JANE · 2018 to 2023
$1.1M
Eunice Kennedy Shriver National Institute of Child Health and Human Development R01-HD-059835NICHD NIH HHS R01 HD059835NIMHD NIH HHS T37 MD001449NIMHD NIH HHS T37-MD-001449NIMH NIH HHS K23 MH115169
6 · The paper itself

Abstract

backgroundPrevious studies suggest sleep quality and obstructive sleep apnea (OSA) may be associated with psychiatric symptoms, including depression, anxiety, and posttraumatic stress disorder (PTSD). However, few studies have examined the relationship between sleep quality and OSA with maternal psychiatric symptoms during pregnancy, a state of vulnerability to these disorders.

objectiveThe objective of our study is to examine the association between poor sleep quality and sleep apnea with antepartum depression, anxiety, and PTSD among pregnant women.

methodsA cross-sectional study was conducted among women seeking prenatal care in Lima, Peru. Sleep quality was measured using the Pittsburgh Sleep Quality Index, and the Berlin questionnaire was used to identify women at high risk for OSA. Depression, generalized anxiety, and PTSD symptoms were measured using the Patient Health Questionnaire-9, Generalized Anxiety Disorder Assessment, and PTSD Checklist - Civilian Version. Multivariate logistic regression procedures were used to estimate adjusted odds ratios (aOR) and 95% confidence intervals (95% CI).

resultsApproximately 29.0X% of women had poor sleep quality, and 6.2% were at high risk for OSA. The prevalence of psychiatric symptoms was high in this cohort with 25.1%, 32.5%, and 30.9% of women reporting symptoms of antepartum depression, antepartum anxiety, and PTSD, respectively. Women with poor sleep quality had higher odds of antepartum depression (aOR = 3.28; 95%CI: 2.64-4.07), generalized anxiety (aOR = 1.94; 95%CI: 1.58-2.38), and PTSD symptoms (aOR = 2.81; 95% CI: 2.28-3.46) as compared with women who reported good sleep quality. Women with a high risk of OSA had higher odds of antepartum depression (aOR = 2.36; 95% CI: 1.57-3.56), generalized anxiety (aOR = 2.02, 95% CI: 1.36-3.00), and PTSD symptoms (aOR = 2.14; 95%CI: 1.43-3.21) as compared with those with a low risk of sleep apnea.

conclusionsPoor sleep quality and high risk of OSA are associated with antepartum depression, generalized anxiety, and PTSD symptoms among pregnant women. Further characterizations of the associations of these prevalent sleep, mood, and anxiety conditions among pregnant women could aid in evaluating and delivering optimal perinatal care to women with these comorbidities.

Indexed as

Pregnancy ComplicationsSleep Apnea, ObstructiveAnxietyAnxiety DisordersCross-Sectional StudiesDepressionFemaleHumansPregnancySleep QualityAnxietyDepressionPosttraumatic stress disorderPregnancySleep apneaSleep quality

Identifiers

PMID35596848
PMCPMC9250423
OpenAlexW4281250133

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.