Evidence map›Paper›PMID 35596741›Full record

ReviewThe Journal of physiology2022

Insights on gastrointestinal motility through the use of optogenetic sensors and actuators.

Bernard T Drumm, Caroline A Cobine, Salah A Baker

Open access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The Journal of physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Orai storeoperated CaChannels (Austin, Tex.) · 2025
    Review
  2. Article
  3. Article
  4. Article
  5. Insights Into Gastrointestinal Motility Through the Use of Optogenetic Sensors.Journal of neurogastroenterology and motility · 2024
    Article
  6. Neuroimmunophysiology of the gastrointestinal tract.American journal of physiology. Gastrointestinal and liver physiology · 2024
    Review
  7. Article
  8. CaPhysiological reviews · 2024
    Review
  9. Article
  10. Article
  11. The enteric nervous system.Physiological reviews · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Bernard T DrummSmooth Muscle Research Centre, Department of Life and Health Science, Dundalk Institute of Technology, Dundalk, Ireland.ORCID 0000-0002-4762-844X
Caroline A CobineDepartment of Physiology and Cell Biology, University of Nevada, Reno School of Medicine, Reno, NV, USA.ORCID 0000-0002-2871-3825
Salah A BakerDepartment of Physiology and Cell Biology, University of Nevada, Reno School of Medicine, Reno, NV, USA.
University of Nevada, Reno · US

Funding

Control of motility in the internal anal sphincterR01DK078736 · NIDDK · UNIVERSITY OF NEVADA RENO · PI KEEF, KATHLEEN D · 2010 to 2019
$3.4M
Role of interstitial cells of Cajal in patterned colonic motor activityR01DK120759 · NIDDK · UNIVERSITY OF NEVADA RENO · PI Sal Baker, KENTON M SANDERS · 2019 to 2026
$3.4M
Control of motility in the lower esophageal sphincterR01DK129528 · NIDDK · UNIVERSITY OF NEVADA RENO · PI COBINE, CAROLINE ANN · 2021 to 2025
$2.1M
NIDDK NIH HHS R01 DK078736NIDDK NIH HHS R01 DK120759NIDDK NIH HHS R01 DK129528
6 · The paper itself

Abstract

The muscularis of the gastrointestinal (GI) tract consists of smooth muscle cells (SMCs) and various populations of interstitial cells of Cajal (ICC), platelet-derived growth factor receptor α

Indexed as

Interstitial Cells of CajalReceptor, Platelet-Derived Growth Factor alphaAnimalsCalmodulinGastrointestinal MotilityMiceMuscle, SmoothOptogeneticsCalmodulinReceptor, Platelet-Derived Growth Factor alphaanoctamin-1 channelsCa2+ signallingchannelrhodopsinsenteric neurotransmissionGCaMPgliainterstitial cells of CajaloptogeneticsSIP syncytiumsmooth muscle cells

Identifiers

PMID35596741
PMCPMC9250614
OpenAlexW4281256584

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.