Evidence map›Paper›PMID 35596698›Full record

ArticleBJOG : an international journal of obstetrics and gynaecology2022

Association between pelvic pain bothersomeness and pain sensitivity: A community-based cross-sectional study of young adult females in the Raine Study.

Darren Beales, Renata Asinelli, Marit Klokset, Lindsay O'Kane, Tonje Urstad, Emma Wise, Juliana Zabatiero, Judith Thompson, Jennifer Pontre, Robert Waller

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In one paragraph

Article in BJOG : an international journal of obstetrics and gynaecology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Darren BealesCurtin enAble Institute and Curtin School of Allied Health, Curtin University, Perth, Western Australia, Australia.ORCID 0000-0002-7176-4644
Renata AsinelliCurtin enAble Institute and Curtin School of Allied Health, Curtin University, Perth, Western Australia, Australia.
Marit KloksetCurtin enAble Institute and Curtin School of Allied Health, Curtin University, Perth, Western Australia, Australia.
Lindsay O'KaneCurtin enAble Institute and Curtin School of Allied Health, Curtin University, Perth, Western Australia, Australia.
Tonje UrstadCurtin enAble Institute and Curtin School of Allied Health, Curtin University, Perth, Western Australia, Australia.
Emma WiseCurtin enAble Institute and Curtin School of Allied Health, Curtin University, Perth, Western Australia, Australia.
Juliana ZabatieroCurtin enAble Institute and Curtin School of Allied Health, Curtin University, Perth, Western Australia, Australia.
Judith ThompsonCurtin enAble Institute and Curtin School of Allied Health, Curtin University, Perth, Western Australia, Australia.
Jennifer PontreKing Edward Memorial Hospital, Perth, Western Australia, Australia.ORCID 0000-0003-3244-4039
Robert WallerCurtin enAble Institute and Curtin School of Allied Health, Curtin University, Perth, Western Australia, Australia.

Funding

Curtin University of TechnologyEdith Cowan UniversityMurdoch UniversityNHMRC 1021855NHMRC 1027449NHMRC 1044840Raine Medical Research FoundationTelethon Kids InstituteThe University of Notre Dame AustraliaUWAWomen and Infants Research Foundation
6 · The paper itself

Abstract

objectivePelvic pain has been associated with augmented nociceptive processing, but large studies controlling for multiple potential confounding factors are lacking. This study investigated the association between pelvic pain bothersomeness and pain sensitivity in young adult women, accounting for potential confounding factors.

designCross-sectional study.

settingCommunity-dwelling sample. POPULATION: The Raine Study Gen2-22 year follow-up (n = 475).

main outcome measuresThe experience of bothersomeness related to pelvic pain was determined from a question in the Urogenital Distress Inventory short form. Pain sensitivity was measured using pressure pain and cold pain thresholds. Potential confounding factors included ethnicity, marital status, highest level of education, income, waist-hip ratio, level of activity, sleep quality, smoking, comorbidity history, C-reactive protein level, musculoskeletal pain experience and psychological distress.

resultsThree hundred and sixty-two women (76.2%) reported no pelvic pain bothersomeness, 74 (15.6%) reported mild pelvic pain bothersomeness and 39 (8.2%) reported moderate-severe pelvic pain bothersomeness. After adjusting for marital status (and test site), moderate-severe pelvic pain bothersomeness was associated with a lower pressure pain threshold (i.e. greater pressure pain sensitivity) (coefficient -51.46, 95% CI -98.06 to -4.86, p = 0.030). After adjusting for smoking, moderate-severe pelvic pain bothersomeness was also associated with a higher cold pain threshold (i.e. greater cold pain sensitivity) (coefficient 4.35, 95% CI 0.90-7.79, p = 0.014).

conclusionsThis study suggests augmented nociceptive processing as a contributing factor in pelvic pain bothersomeness for some women. Thorough assessment of women who present clinically with pelvic pain should consider pain sensitivity as a potential contributing factor to their presentation.

Indexed as

C-Reactive ProteinPain ThresholdCross-Sectional StudiesFemaleHumansPain MeasurementPelvic PainYoung AdultC-Reactive Proteinhyperalgesiapelvic painquantitative sensory testRaine Studysensitivity

Identifiers

PMID35596698
PMCPMC9796573

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.