Evidence map›Paper›PMID 35596608›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2022

Micro-Gel Ensembles for Accelerated Healing of Chronic Wound via pH Regulation.

Tingting Cui, Jiafei Yu, Cai-Feng Wang, Su Chen, Qing Li, Kun Guo, Renkun Qing, Gefei Wang, Jianan Ren

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers.

0numbers the graph read from it
0cells of the map it votes in
79citing papers in PubMed
23.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

79 citing papers in PubMed, 253 citations in OpenAlex.

  1. Article
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  6. Negative Pressure Wound Therapy Modulates Wound pH and Bacterial Invasion inPlastic and reconstructive surgery. Global open · 2026
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19 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Tingting CuiState Key Laboratory of Materials-Oriented Chemical Engineering, College of Chemical Engineering, Jiangsu Key Laboratory of Fine Chemicals and Functional Polymer Materials, Nanjing Tech University, Nanjing, 210009, P. R. China.
Jiafei YuDepartment of General Surgery, Jinling Hospital, Nanjing Medical University, Nanjing, 210002, China.
Cai-Feng WangState Key Laboratory of Materials-Oriented Chemical Engineering, College of Chemical Engineering, Jiangsu Key Laboratory of Fine Chemicals and Functional Polymer Materials, Nanjing Tech University, Nanjing, 210009, P. R. China.
Su ChenState Key Laboratory of Materials-Oriented Chemical Engineering, College of Chemical Engineering, Jiangsu Key Laboratory of Fine Chemicals and Functional Polymer Materials, Nanjing Tech University, Nanjing, 210009, P. R. China.ORCID 0000-0002-3799-469X
Qing LiState Key Laboratory of Materials-Oriented Chemical Engineering, College of Chemical Engineering, Jiangsu Key Laboratory of Fine Chemicals and Functional Polymer Materials, Nanjing Tech University, Nanjing, 210009, P. R. China.
Kun GuoDepartment of General Surgery, Jinling Hospital, Nanjing Medical University, Nanjing, 210002, China.
Renkun QingState Key Laboratory of Materials-Oriented Chemical Engineering, College of Chemical Engineering, Jiangsu Key Laboratory of Fine Chemicals and Functional Polymer Materials, Nanjing Tech University, Nanjing, 210009, P. R. China.
Gefei WangDepartment of General Surgery, Jinling Hospital, Nanjing Medical University, Nanjing, 210002, China.
Jianan RenDepartment of General Surgery, Jinling Hospital, Nanjing Medical University, Nanjing, 210002, China.
Nanjing Tech University · CNNanjing General Hospital of Nanjing Military Command · CN

Funding

Animal Ethical Committee of Jinling Hospital 2018GKJDWLS-03-127Declaration of HelsinkiNational Natural Science Foundation of China 21736006National Natural Science Foundation of China 21908103National Natural Science Foundation of China 21978132National Natural Science Foundation of China 81870396Priority Academic Program Development of Jiangsu Higher Education InstitutionsSocial Development Projects for Key Research and Development Plan in Jiangsu Province BE2017725
6 · The paper itself

Abstract

The pH value in the wound milieu plays a key role in cellular processes and cell cycle processes involved in the process of wound healing. Here, a microfluidic assembly technique is employed to fabricate micro-gel ensembles that can precisely tune the pH value of wound surface and accelerate wound healing. The micro-gel ensembles consist of poly (hydroxypropyl acrylate-co-acrylic acid)-magnesium ions (poly-(HPA-co-AA)-Mg

Indexed as

HydrogelsWound HealingHydrogen-Ion ConcentrationHydrogelsaccelerated wound healingchronic woundmicrofluidic assemblymicro-gel ensembleswound pH regulation

Identifiers

PMID35596608
PMCPMC9353480
OpenAlexW4281250463

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.