Evidence map›Paper›PMID 35596604›Full record

ArticleJournal of cachexia, sarcopenia and muscle2022

Muscle mass and estimates of renal function: a longitudinal cohort study.

Dion Groothof, Adrian Post, Harmke A Polinder-Bos, Nicole S Erler, Jose L Flores-Guerrero, Jenny E Kootstra-Ros, Robert A Pol, Martin H de Borst, Ron T Gansevoort, Reinold O B Gans and 6 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of cachexia, sarcopenia and muscle, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
8.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 70 citations in OpenAlex.

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  9. Review
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  11. Lean body mass index and hypertension risk in men: a nationwide epidemiological cohort study.Hypertension research : official journal of the Japanese Society of Hypertension · 2026
    Article
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  16. CKD in Indigenous Populations in Kerala, India.Kidney international reports · 2026
    Article
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  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 2 countries.

Dion GroothofDepartment of Internal Medicine, Division of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.ORCID 0000-0002-1886-4451
Adrian PostDepartment of Internal Medicine, Division of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.ORCID 0000-0001-8645-1627
Harmke A Polinder-BosDepartment of Internal Medicine, Erasmus Medical Center, Erasmus University Rotterdam, Rotterdam, the Netherlands.ORCID 0000-0002-7458-725X
Nicole S ErlerDepartment of Biostatistics, Erasmus Medical Center, Erasmus University Rotterdam, Rotterdam, the Netherlands.ORCID 0000-0002-9370-6832
Jose L Flores-GuerreroDepartment of Internal Medicine, Division of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.ORCID 0000-0002-6094-2206
Jenny E Kootstra-RosDepartment of Laboratory Medicine, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.ORCID 0000-0002-1394-513X
Robert A PolDepartment of Surgery, Division of Vascular and Transplantation Surgery, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.ORCID 0000-0002-2236-5233
Martin H de BorstDepartment of Internal Medicine, Division of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.ORCID 0000-0002-4127-8733
Ron T GansevoortDepartment of Internal Medicine, Division of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.ORCID 0000-0002-3223-0906
Reinold O B GansDepartment of Internal Medicine, Division of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.ORCID 0000-0001-5481-2387
Daan KremerDepartment of Internal Medicine, Division of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.ORCID 0000-0003-0011-115X
Lyanne M KienekerDepartment of Internal Medicine, Division of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.ORCID 0000-0002-8028-6488
Arjola BanoInstitute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland.ORCID 0000-0003-0956-7145
Taulant MukaInstitute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland.ORCID 0000-0003-3235-3073
Oscar H FrancoInstitute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland.ORCID 0000-0002-4606-4929
Stephan J L BakkerDepartment of Internal Medicine, Division of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.ORCID 0000-0003-3356-6791
University Medical Center Groningen · NLUniversity of Bern · CHErasmus MC · NL

Funding

Dutch Kidney Foundation E.033
6 · The paper itself

Abstract

backgroundCreatinine is the most widely used test to estimate the glomerular filtration rate (GFR), but muscle mass as key determinant of creatinine next to renal function may confound such estimates. We explored effects of 24-h height-indexed creatinine excretion rate (CER index) on GFR estimated with creatinine (eGFR

methodsWe included 8076 adults enrolled in the PREVEND study. Discordant classification was defined as not having eGFR

resultsMean (SD) CER index was 8.0 (1.7) and 6.1 (1.3) mmol/24 h per meter in male and female participants, respectively (P

conclusionsLow muscle mass may cause considerable overestimation of single measurements of eGFR

Indexed as

Muscular DiseasesRenal Insufficiency, ChronicAdultAgedCohort StudiesCreatinineCystatin CFemaleHumansKidneyLongitudinal StudiesMaleMiddle AgedMusclesCreatinineCystatin CBiasCreatinineCystatin CGeneral populationMuscle massRenal function

Identifiers

PMID35596604
PMCPMC9398222
OpenAlexW4281256884

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.