Evidence map›Paper›PMID 35596105›Full record

ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2022

High-power short-duration ablation index-guided pulmonary vein isolation protocol using a single catheter.

Patrick Badertscher, Sven Knecht, Florian Spies, Gian Völlmin, Beat Schaer, Nicolas Schärli, Flurina Bosshard, Stefan Osswald, Christian Sticherling, Michael Kühne

Open access · hybridAbstract read
In one paragraph

Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Anterior mitral isthmus line using pulsed-field ablation with the pentaspline catheter or radiofrequency ablation: procedural characteristics, safety, and mid-term outcomes.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Article
  3. Article
  4. Contemporary Trends in Pulsed Field Ablation for Cardiac Arrhythmias.Journal of cardiovascular development and disease · 2024
    Review
  5. Comparing cryoballoon and contact-force guided radiofrequency ablation in pulmonary vein isolation for atrial fibrillation in patients with hypertrophic cardiomyopathy.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2024
    Article
  6. Article
  7. Repeat catheter ablation after very late recurrence of atrial fibrillation after pulmonary vein isolation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Article
  8. Silent cerebral lesions following catheter ablation for atrial fibrillation: a state-of-the-art review.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 1 institution in 2 countries.

Patrick BadertscherDepartment of Cardiology, University Hospital Basel, Petersgraben 4, 4031, Basel, Switzerland.ORCID http://orcid.org/0000-0001-9751-0557
Sven KnechtDepartment of Cardiology, University Hospital Basel, Petersgraben 4, 4031, Basel, Switzerland. sven.knecht@ubs.ch.
Florian SpiesDepartment of Cardiology, University Hospital Basel, Petersgraben 4, 4031, Basel, Switzerland.
Gian VöllminDepartment of Cardiology, University Hospital Basel, Petersgraben 4, 4031, Basel, Switzerland.
Beat SchaerDepartment of Cardiology, University Hospital Basel, Petersgraben 4, 4031, Basel, Switzerland.
Nicolas SchärliDepartment of Cardiology, University Hospital Basel, Petersgraben 4, 4031, Basel, Switzerland.
Flurina BosshardDepartment of Cardiology, University Hospital Basel, Petersgraben 4, 4031, Basel, Switzerland.
Stefan OsswaldDepartment of Cardiology, University Hospital Basel, Petersgraben 4, 4031, Basel, Switzerland.
Christian SticherlingDepartment of Cardiology, University Hospital Basel, Petersgraben 4, 4031, Basel, Switzerland.
Michael KühneDepartment of Cardiology, University Hospital Basel, Petersgraben 4, 4031, Basel, Switzerland.
University Hospital of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCatheter ablation for atrial fibrillation (AF) is the most commonly performed electrophysiological procedure. To improve healthcare utilization, we aimed to compare the efficacy, efficiency, and safety of a minimalistic, streamlined single catheter ablation approach using a high-power short-duration ablation index-guided protocol (HPSD) vs. a control single-catheter protocol (SP).

methodsPulmonary vein isolation (PVI) with a single transseptal puncture without a multipolar mapping catheter was performed in 91 patients. Left atrial mapping was performed with the ablation catheter, only. Pacing maneuvers were used to confirm exit block. Procedural characteristics and success rates were compared using HPSD (n = 34) vs. a control (n = 57) ablation protocol. Freedom from recurrence was defined as a 1-year absence of AF episodes > 30 s, beyond the 3-month blanking period.

resultsUsing the HPSD protocol the median procedure and RF ablation time were significantly shorter compared to the SP, 84 (IQR 76-100) vs. 118 min (IQR 104-141) and 1036 (898-1184) vs. 1949s (IQR 1693-2261), respectively, p < .001 for all. First-pass PVI was achieved using the HPSD protocol in 88% and using the SP in 87% of patients, p = 1.0. No procedural complications were observed. High-sensitivity cardiac troponin levels were significantly higher in patients using the HPSD protocol compared to the SP. At 12 months follow-up, 87% patients remained free from AF with no differences between groups.

conclusionsA minimalistic, HPSD ablation index-guided PVI with a single-catheter approach is very efficient, safe, and associated with excellent clinical outcomes at 1 year.

Indexed as

Pulmonary VeinsCardiac ElectrophysiologyHumansAtrial fibrillationCatheter ablationEfficacy

Identifiers

PMID35596105
PMCPMC9726791
OpenAlexW4281250186

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.