Evidence map›Paper›PMID 35596097›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2022

Antimicrobial activity of ceftazidime-avibactam and comparators against Pseudomonas aeruginosa and Enterobacterales collected in Croatia, Czech Republic, Hungary, Poland, Latvia and Lithuania: ATLAS Surveillance Program, 2019.

V Adámková, I Mareković, J Szabó, L Pojnar, S Billová, S Horvat Herceg, A Kuraieva, B Możejko-Pastewka

Open access · hybridAbstract read
In one paragraph

Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
0.6field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Global epidemiology of carbapenem-resistantJAC-antimicrobial resistance · 2026
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  4. Increased Prevalence of Multidrug-ResistantLife (Basel, Switzerland) · 2026
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  5. Activity of cefiderocol againstMicrobiology spectrum · 2025
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 4 countries.

V AdámkováInstitute of Medical Biochemistry and Laboratory Diagnostics, General University Hospital, Prague, Czech Republic.
I MarekovićDepartment of Clinical and Molecular Microbiology, University Hospital Centre Zagreb, Zagreb, Croatia.
J SzabóDepartment of Medical Microbiology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
L PojnarDepartment of Microbiology, University Hospital, Cracow, Poland.
S BillováPfizer, spol. s r.o., Prague, Czech Republic. sabina.billova@pfizer.com.
S Horvat HercegPfizer Croatia, Zagreb, Croatia.
A KuraievaPfizer Export B.V. RO, Kyiv, Ukraine.
B Możejko-PastewkaPfizer Polska Sp. z o.o, Warsaw, Poland.
Cracow University of Technology · PLGeneral University Hospital in Prague · CZInstitute of Economics Zagreb · HRUniversity Hospital Centre Zagreb · HRUniversity of Debrecen · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial susceptibility of clinical isolates collected from sites in central Europe in 2019 was tested by CLSI broth microdilution method and EUCAST breakpoints. Most active were amikacin, ceftazidime-avibactam and colistin; respectively, susceptibility rates among P. aeruginosa (n = 701) were 89.2%, 92.2% and 99.9%; difficult-to-treat (DTR) isolates, 62.5%, 37.5% and 100%; multidrug-resistant (MDR) isolates, 68.3%, 72.9% and 99.5%; meropenem-resistant (MEM-R), metallo-β-lactamase-negative (MBL-negative) isolates, 72.8%, 78.6% and 100%. Among Enterobacterales (n = 1639), susceptibility to ceftazidime-avibactam, colistin and tigecycline was ≥ 97.9%; MDR Enterobacterales, 96.8%, 94.4% and 100%, respectively; DTR isolates, ≥ 76.2% to ceftazidime-avibactam and colistin; MEM-R, MBL-negative isolates, ≥ 90.0% to ceftazidime-avibactam and colistin.

Indexed as

ColistinPseudomonas aeruginosaAnti-Bacterial AgentsAzabicyclo CompoundsCeftazidimeCroatiaCzech RepublicDrug CombinationsEnterobacteriaceaeHumansHungaryLatviaLithuaniaMeropenemMicrobial Sensitivity TestsPolandAnti-Bacterial Agentsavibactam, ceftazidime drug combinationAzabicyclo CompoundsCeftazidimeColistinDrug CombinationsMeropenemAntimicrobial surveillanceATLASCeftazidime-avibactamDifficult-to-treatEnterobacteralesPseudomonas aeruginosa

Identifiers

PMID35596097
PMCPMC9135846
OpenAlexW4281249697

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.