Evidence map›Paper›PMID 35595880›Full record

ArticleFish physiology and biochemistry2022

Testicular miRNAs and tsRNAs provide insight into gene regulation during overwintering and reproduction of Onychostoma macrolepis.

Guofan Peng, Chao Zhu, Qingfang Sun, Jincan Li, Yining Chen, Yingjie Guo, Hong Ji, Fangxia Yang, Wuzi Dong

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In one paragraph

Article in Fish physiology and biochemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Guofan Peng *College of Animal Science and Technology, Northwest A&F University, No. 22 Xinong Road, Shaanxi, 712100, China.
Chao Zhu *College of Animal Science and Technology, Northwest A&F University, No. 22 Xinong Road, Shaanxi, 712100, China.
Qingfang SunCollege of Animal Science and Technology, Northwest A&F University, No. 22 Xinong Road, Shaanxi, 712100, China.
Jincan LiCollege of Animal Science and Technology, Northwest A&F University, No. 22 Xinong Road, Shaanxi, 712100, China.
Yining ChenCollege of Animal Science and Technology, Northwest A&F University, No. 22 Xinong Road, Shaanxi, 712100, China.
Yingjie GuoBiology Research Centre of Qin Mountains Wildlife, Northwest A&F University, No. 22 Xinong Road, Shaanxi, 712100, China.
Hong JiCollege of Animal Science and Technology, Northwest A&F University, No. 22 Xinong Road, Shaanxi, 712100, China.
Fangxia YangBiology Research Centre of Qin Mountains Wildlife, Northwest A&F University, No. 22 Xinong Road, Shaanxi, 712100, China. yangfangxia@nwsuaf.edu.cn.
Wuzi DongCollege of Animal Science and Technology, Northwest A&F University, No. 22 Xinong Road, Shaanxi, 712100, China. dongwuzi@nwsuaf.edu.cn.
Northwest A&F University · CN

Funding

China Se-enriched industry research institute 2021FXZX04-01
6 · The paper itself

Abstract

The late overwintering period and breeding period are two important developmental stages of testis in Onychostoma macrolepis. Small non-coding RNAs (sncRNAs) are well-known regulators of biological processes associated with numerous biological processes. This study aimed to elucidate the roles of four sncRNA classes (microRNAs [miRNAs], Piwi-interacting RNAs [piRNAs], tRNA-derived small RNAs [tsRNAs], and rRNA-derived small RNAs [rsRNAs]) across testes in the late overwintering period (in March) and breeding period (in June) by high-throughput sequencing. The testis of O. macrolepis displayed the highest levels of piRNAs and lowest levels of rsRNAs. Compared with miRNAs and tsRNAs in June, tsRNAs in March had a higher abundance, while miRNAs in March had a much lower abundance. Bioinformatics analysis identified 1,362 and 1,340 differentially expressed miRNAs and tsRNAs, respectively. Further analysis showed that miR-200-1, miR-143-1, tRFi-Lys-CTT-1, and tRFi-Glu-CTC-1 could play critical roles during the overwintering and breeding periods. Our findings provided an unprecedented insight to reveal the epigenetic mechanism underlying the overwintering and reproduction process of male O. macrolepis.

Indexed as

CyprinidaeMicroRNAsRNA, Small UntranslatedAnimalsGene Expression RegulationMaleReproductionTestisMicroRNAsRNA, Small UntranslatedAtypical cavefishBioinformatics analysisOnychostoma macrolepisSmall non-coding RNAsTestis

Identifiers

PMID35595880
OpenAlexW4281259024

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.