Evidence map›Paper›PMID 35595847›Full record

ArticleScientific reports2022

In vitro and in ovo impact of the ionic dissolution products of boron-doped bioactive silicate glasses on cell viability, osteogenesis and angiogenesis.

Simon Decker, Marcela Arango-Ospina, Felix Rehder, Arash Moghaddam, Rolf Simon, Christian Merle, Tobias Renkawitz, Aldo R Boccaccini, Fabian Westhauser

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 47 citations in OpenAlex.

  1. Review
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  4. RSC advances · 2024
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  5. Investigation ofRSC advances · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Simon DeckerDepartment of Orthopaedics, Heidelberg University Hospital, Schlierbacher Landstraße 200a, 69118, Heidelberg, Germany.
Marcela Arango-OspinaInstitute of Biomaterials, University of Erlangen-Nuremberg, Cauerstr. 6, 91058, Erlangen, Germany.
Felix RehderDepartment of Orthopaedics, Heidelberg University Hospital, Schlierbacher Landstraße 200a, 69118, Heidelberg, Germany.
Arash MoghaddamOrthopedic and Trauma Surgery, Frohsinnstraße 12, 63739, Aschaffenburg, Germany.
Rolf SimonDepartment of Orthopaedics, Heidelberg University Hospital, Schlierbacher Landstraße 200a, 69118, Heidelberg, Germany.
Christian MerleDepartment of Orthopaedics, Heidelberg University Hospital, Schlierbacher Landstraße 200a, 69118, Heidelberg, Germany.
Tobias RenkawitzDepartment of Orthopaedics, Heidelberg University Hospital, Schlierbacher Landstraße 200a, 69118, Heidelberg, Germany.
Aldo R BoccacciniInstitute of Biomaterials, University of Erlangen-Nuremberg, Cauerstr. 6, 91058, Erlangen, Germany.
Fabian WesthauserDepartment of Orthopaedics, Heidelberg University Hospital, Schlierbacher Landstraße 200a, 69118, Heidelberg, Germany. Fabian.Westhauser@med.uni-heidelberg.de.
University Hospital Heidelberg · DEFriedrich-Alexander-Universität Erlangen-Nürnberg · DEHeidelberg University · DEKlinikum Aschaffenburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to the pivotal role of angiogenesis in bone regeneration, the angiogenic properties of biomaterials are of high importance since they directly correlate with the biomaterials' osteogenic potential via 'angiogenic-osteogenic coupling' mechanisms. The impact of bioactive glasses (BGs) on vascularization can be tailored by incorporation of biologically active ions such as boron (B). Based on the ICIE16-BG composition (in mol%: 49.5 SiO

Indexed as

BoronOsteogenesisBiocompatible MaterialsCell SurvivalGlassIonsSilicatesSilicon DioxideSolubilityBiocompatible MaterialsBoronIonsSilicatesSilicon Dioxide

Identifiers

PMID35595847
PMCPMC9122978
OpenAlexW4280558908

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.