Evidence map›Paper›PMID 35595540›Full record

ArticleCerebral cortex (New York, N.Y. : 1991)2023

Network-specific selectivity of functional connections in the neonatal brain.

Chad M Sylvester, Sydney Kaplan, Michael J Myers, Evan M Gordon, Rebecca F Schwarzlose, Dimitrios Alexopoulos, Ashley N Nielsen, Jeanette K Kenley, Dominique Meyer, Qiongru Yu and 8 more

Abstract read
In one paragraph

Article in Cerebral cortex (New York, N.Y. : 1991), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed.

  1. Review
  2. Article
  3. Dynamics of the attentional blink in preverbal infants.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Article
  5. Individualized Mapping of Functional Brain Networks in Older Adulthood.bioRxiv : the preprint server for biology · 2026
    Article
  6. Article
  7. Article
  8. Social Determinants of Health, the developing brain, and risk and resilience for psychopathology.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
  9. Considerations for conducting developmental neuroimaging research on mental health topics.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
  10. Article
  11. Article
  12. Precision functional imaging in infants using multi-echo fMRI at 7T.bioRxiv : the preprint server for biology · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Structure-function coupling in the first month of life: Associations with age and attention.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Chad M SylvesterDepartment of Psychiatry, Washington University, 660 S. Euclid Avenue, St. Louis, MO 63110, USA.
Sydney KaplanDepartment of Neurology, Washington University, 660 S. Euclid Avenue, St. Louis, MO 63110, USA.
Michael J MyersDepartment of Psychiatry, Washington University, 660 S. Euclid Avenue, St. Louis, MO 63110, USA.
Evan M GordonDepartment of Radiology, Washington University, 660 S. Euclid Avenue, St. Louis, MO 63110, USA.ORCID 0000-0002-2276-5237
Rebecca F SchwarzloseDepartment of Psychiatry, Washington University, 660 S. Euclid Avenue, St. Louis, MO 63110, USA.
Dimitrios AlexopoulosDepartment of Neurology, Washington University, 660 S. Euclid Avenue, St. Louis, MO 63110, USA.
Ashley N NielsenDepartment of Neurology, Washington University, 660 S. Euclid Avenue, St. Louis, MO 63110, USA.ORCID 0000-0002-7148-8256
Jeanette K KenleyDepartment of Neurology, Washington University, 660 S. Euclid Avenue, St. Louis, MO 63110, USA.
Dominique MeyerDepartment of Neurology, Washington University, 660 S. Euclid Avenue, St. Louis, MO 63110, USA.
Qiongru YuJoint Doctoral Program in Clinical Psychology, San Diego State University/University of California San Diego, 6363 Alvarado Court, Suite 103, San Diego, CA 92120, USA.
Alice M GrahamDepartment of Psychiatry, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA.
Damien A FairMasonic Institute for the Developing Brain, Department of Pediatrics, and Institute of Child Development, University of Minnesota, 2025 E. River Parkway, Minneapolis, MN 55414, USA.
Barbara B WarnerDepartment of Pediatrics, Washington University, 660 S. Euclid Avenue, St. Louis, MO 63110, USA.
Deanna M BarchDepartment of Psychiatry, Washington University, 660 S. Euclid Avenue, St. Louis, MO 63110, USA.
Cynthia E RogersDepartment of Psychiatry, Washington University, 660 S. Euclid Avenue, St. Louis, MO 63110, USA.
Joan L LubyDepartment of Psychiatry, Washington University, 660 S. Euclid Avenue, St. Louis, MO 63110, USA.
Steven E PetersenDepartment of Neurology, Washington University, 660 S. Euclid Avenue, St. Louis, MO 63110, USA.
Christopher D SmyserDepartment of Neurology, Washington University, 660 S. Euclid Avenue, St. Louis, MO 63110, USA.

Funding

Early Life Adversity, Biological Embedding, and Risk for Developmental Precursors of Mental DisordersR01MH113883 · NIMH · WASHINGTON UNIVERSITY · PI JOAN L. LUBY, Christopher Daniel Smyser · 2018 to 2026
$20.6M
Supplement to Prevention Research Center: Parenting Among Women Who Are Opioid Users, Project 2P50DA048756 · NIDA · UNIVERSITY OF OREGON · PI FISHER, PHILIP A · 2019 to 2023
$18.0M
WUIDDRC Supplement-Supporting the health and well-being of children with intellectual and developmental disability during COVID-19 pandemicP50HD103525 · NICHD · WASHINGTON UNIVERSITY · PI JOSEPH D DOUGHERTY, Natasha Marrus · 2020 to 2026
$15.5M
NEUROIMAGING IN EARLY ONSET DEPRESSION: LONGITUDINAL ASSESSMENT OF BRAIN CHANGESR01MH090786 · NIMH · WASHINGTON UNIVERSITY · PI GILBERT, KIRSTEN, WHALEN, DIANA J · 2010 to 2025
$10.4M
Identification of outcome-based sub-populations using deep phenotyping and precision functional mapping across ADHD and ASDR01MH096773 · NIMH · UNIVERSITY OF MINNESOTA · PI DOSENBACH, NICO, FAIR, DAMIEN A · 2012 to 2024
$9.4M
The Transgenerational Influence of Discrimination on Mental HealthU01DA055363 · NIDA · OREGON HEALTH & SCIENCE UNIVERSITY · PI Alice M Graham, Elinor L. Sullivan · 2021 to 2026
$8.8M
Pre- and Postnatal Exposure Periods for Child Health: Common Risks and Shared MechanismsUG3OD023349 · OD · UNIVERSITY OF ROCHESTER · PI BARRETT, EMILY S, MILLER, RICHARD KERMIT · 2016 to 2024
$7.0M
Neonatal Brain Activity and Risk for Anxiety Disorders in Early ChildhoodR01MH122389 · NIMH · WASHINGTON UNIVERSITY · PI Chad Michael Sylvester · 2020 to 2026
$3.9M
Brain trajectories in ADHDR01MH115357 · NIMH · OREGON HEALTH & SCIENCE UNIVERSITY · PI FAIR, DAMIEN A, NIGG, JOEL T · 2017 to 2021
$3.8M
THE PRETERM BEHAVIORAL PHENOTYPE: TRAJECTORIES OF PSYCHOPATHOLOGY & CHANGES IN CEREBRAL CONNECTIVITYR01MH113570 · NIMH · WASHINGTON UNIVERSITY · PI ROGERS, CYNTHIA ELISE, SMYSER, CHRISTOPHER DANIEL · 2017 to 2021
$3.1M
ATTENTION AND RELATED FUNCTIONAL BRAIN NETWORKS IN PEDIATRIC ANXIETY DISORDERSK23MH109983 · NIMH · WASHINGTON UNIVERSITY · PI SYLVESTER, CHAD MICHAEL · 2016 to 2020
$1.1M
2/7: Longitudinal evaluation of the impact of the COVID-19 pandemic on high-risk new and expectant mothersR34DA050291 · NIDA · OREGON HEALTH & SCIENCE UNIVERSITY · PI FAIR, DAMIEN A, GRAHAM, ALICE M · 2019 to 2021
$977k
NICHD NIH HHS P50 HD103525NIDA NIH HHS P50 DA048756NIDA NIH HHS R34 DA050291NIDA NIH HHS U01 DA055363NIH HHS K23 MH109983NIH HHS UG3 OD023349NIMH NIH HHS K23 MH105179NIMH NIH HHS K23 MH109983NIMH NIH HHS R01 MH090786NIMH NIH HHS R01 MH096773NIMH NIH HHS R01 MH113570NIMH NIH HHS R01 MH113883NIMH NIH HHS R01 MH115357NIMH NIH HHS R01 MH122389NINDS NIH HHS K02 NS089852
6 · The paper itself

Abstract

The adult human brain is organized into functional brain networks, groups of functionally connected segregated brain regions. A key feature of adult functional networks is long-range selectivity, the property that spatially distant regions from the same network have higher functional connectivity than spatially distant regions from different networks. Although it is critical to establish the status of functional networks and long-range selectivity during the neonatal period as a foundation for typical and atypical brain development, prior work in this area has been mixed. Although some studies report distributed adult-like networks, other studies suggest that neonatal networks are immature and consist primarily of spatially isolated regions. Using a large sample of neonates (n = 262), we demonstrate that neonates have long-range selective functional connections for the default mode, fronto-parietal, and dorsal attention networks. An adult-like pattern of functional brain networks is evident in neonates when network-detection algorithms are tuned to these long-range connections, when using surface-based registration (versus volume-based registration), and as per-subject data quantity increases. These results help clarify factors that have led to prior mixed results, establish that key adult-like functional network features are evident in neonates, and provide a foundation for studies of typical and atypical brain development.

Indexed as

Brain MappingMagnetic Resonance ImagingAdultBrainHumansImage Processing, Computer-AssistedInfant, NewbornNerve NetNeural PathwaysfMRIfunctional connectivityinfantneonatenetworks

Identifiers

PMID35595540
PMCPMC9977389

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.