Evidence map›Paper›PMID 35595182›Full record

ArticleThe British journal of surgery2022

KRAS alterations in colorectal liver metastases: shifting to exon, codon, and point mutations.

Pim B Olthof, Stefan Buettner, Nikolaos Andreatos, Jane Wang, Inger Marie Løes, Doris Wagner, Kazunari Sasaki, Andrea Macher-Beer, Carsten Kamphues, Ioannis Pozios and 17 more

Open access · bronzeAbstract read
In one paragraph

Article in The British journal of surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

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  5. Unveiling the role ofTranslational cancer research · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

27 authors at 15 institutions in 6 countries.

Pim B OlthofDepartment of Surgery, Erasmus University, Rotterdam, the Netherlands.
Stefan BuettnerDepartment of Surgery, Erasmus University, Rotterdam, the Netherlands.
Nikolaos AndreatosDivision of Medical Oncology, Mayo Clinic, Rochester, Minnesota, USA.
Jane WangDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Inger Marie LøesDepartment of Clinical Science, University of Bergen, and Department of Oncology, Haukeland University Hospital, Bergen, Norway.
Doris WagnerDepartment of General Surgery, Medical University of Graz, Graz, Austria.
Kazunari SasakiDepartment of General Surgery, Digestive Disease Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Andrea Macher-BeerDepartment of Pathology, Medical University of Vienna, Vienna, Austria.
Carsten KamphuesDepartment of General and Visceral Surgery, Charité Campus Benjamin Franklin, Berlin, Germany.
Ioannis PoziosDepartment of General and Visceral Surgery, Charité Campus Benjamin Franklin, Berlin, Germany.
Hendrik SeeligerDepartment of General and Visceral Surgery, Charité Campus Benjamin Franklin, Berlin, Germany.
Daisuke MoriokaDepartment of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Katsunori ImaiDepartment of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, Yokohama, Japan.ORCID 0000-0003-0549-1825
Klaus KaczirekDepartment of General Surgery, Medical University of Vienna, Vienna, Austria.
Timothy M PawlikDepartment of Surgery, Ohio State University Wexner Medical Center, Columbus, Ohio, USA.ORCID 0000-0002-7994-9870
George PoultsidesDepartment of Surgery, Stanford University School of Medicine, Stanford, California, USA.
Richard BurkhartDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Itaru EndoDepartment of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, Yokohama, Japan.ORCID 0000-0002-3202-2752
Hideo BabaDepartment of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.ORCID 0000-0002-2999-696X
Peter KornpratDepartment of General Surgery, Medical University of Graz, Graz, Austria.
Federico N AucejoDepartment of General Surgery, Digestive Disease Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Per Eystein LønningDepartment of Clinical Science, University of Bergen, and Department of Oncology, Haukeland University Hospital, Bergen, Norway.ORCID 0000-0002-8890-6303
Katharina BeyerDepartment of General and Visceral Surgery, Charité Campus Benjamin Franklin, Berlin, Germany.
Matthew J WeissDepartment of Surgery, Zucker School of Medicine at Hofstra, Northwell Health Cancer Institute, Lake Success, New York, USA.
Christopher L WolfgangDepartment of Surgery, New York University School of Medicine, New York, New York, USA.
Martin E KreisDepartment of General and Visceral Surgery, Charité Campus Benjamin Franklin, Berlin, Germany.
Georgios A MargonisDepartment of General and Visceral Surgery, Charité Campus Benjamin Franklin, Berlin, Germany.ORCID 0000-0003-4894-5743
Charité - Universitätsmedizin Berlin · DEYokohama City University · JPCleveland Clinic · USErasmus University Rotterdam · NLHaukeland University Hospital · NOJohns Hopkins University · USMedical University of Graz · ATMedical University of Vienna · ATKumamoto University · JPMayo Clinic · USMemorial Sloan Kettering Cancer Center · USNew York University · USNorthwell Health · USStanford University · USThe Ohio State University Wexner Medical Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748NIH HHS P30 CA008748
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Colorectal NeoplasmsLiver NeoplasmsCodonExonsHumansMutationPoint MutationProto-Oncogene Proteins p21(ras)CodonKRAS protein, humanProto-Oncogene Proteins p21(ras)

Identifiers

PMID35595182
PMCPMC9380990
OpenAlexW4225911913

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.