Evidence map›Paper›PMID 35595101›Full record

ArticleThe Journal of biological chemistry2022

Structure, dynamics, and molecular inhibition of the Staphylococcus aureus m

Pamela Sweeney, Ashleigh Galliford, Abhishek Kumar, Dinesh Raju, Naveen B Krishna, Emmajay Sutherland, Caitlin J Leo, Gemma Fisher, Roopa Lalitha, Likith Muthuraj and 8 more

Open access · goldAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Compendium of RNA modifications for bacterial stress adaptation.Microbiology and molecular biology reviews : MMBR · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Effect of NaCl stress on exoproteome profiles ofFrontiers in microbiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 2 institutions in 1 country.

Pamela SweeneySchool of Biology, Biomedical Sciences Research Complex, University of St Andrews, St Andrews, United Kingdom.
Ashleigh GallifordSchool of Biology, Biomedical Sciences Research Complex, University of St Andrews, St Andrews, United Kingdom.
Abhishek KumarKcat Enzymatic Private Limited, Bangalore, India.
Dinesh RajuKcat Enzymatic Private Limited, Bangalore, India.
Naveen B KrishnaKcat Enzymatic Private Limited, Bangalore, India.
Emmajay SutherlandSchool of Biology, Biomedical Sciences Research Complex, University of St Andrews, St Andrews, United Kingdom.
Caitlin J LeoSchool of Biology, Biomedical Sciences Research Complex, University of St Andrews, St Andrews, United Kingdom.
Gemma FisherSchool of Biology, Biomedical Sciences Research Complex, University of St Andrews, St Andrews, United Kingdom.
Roopa LalithaKcat Enzymatic Private Limited, Bangalore, India.
Likith MuthurajKcat Enzymatic Private Limited, Bangalore, India.
Gladstone SigamaniKcat Enzymatic Private Limited, Bangalore, India.
Verena OehlerSchool of Biology, Biomedical Sciences Research Complex, University of St Andrews, St Andrews, United Kingdom.
Silvia SynowskySchool of Biology, Biomedical Sciences Research Complex, University of St Andrews, St Andrews, United Kingdom.
Sally L ShirranSchool of Biology, Biomedical Sciences Research Complex, University of St Andrews, St Andrews, United Kingdom.
Tracey M GlosterSchool of Biology, Biomedical Sciences Research Complex, University of St Andrews, St Andrews, United Kingdom.
Clarissa M CzeksterSchool of Biology, Biomedical Sciences Research Complex, University of St Andrews, St Andrews, United Kingdom.
Pravin KumarKcat Enzymatic Private Limited, Bangalore, India. Electronic address: pravin.k@kcat.co.in.
Rafael G da SilvaSchool of Biology, Biomedical Sciences Research Complex, University of St Andrews, St Andrews, United Kingdom. Electronic address: rgds@st-andrews.ac.uk.
University of St Andrews · GBKleijnen Systematic Reviews (United Kingdom) · GB

Funding

Wellcome TrustWellcome Trust 204821/Z/16/ZWellcome Trust 208980/Z/17/Z
6 · The paper itself

Abstract

The enzyme m

Indexed as

Bacterial ProteinsStaphylococcus aureustRNA MethyltransferasesAdenineCrystallography, X-RayProtein ConformationRNA, TransferS-AdenosylmethionineAdenineBacterial ProteinsRNA, TransferS-AdenosylmethioninetRNA MethyltransferasesRNA methyltransferaseS-adenosylmethionine (SAM)Staphylococcus aureustransfer RNA (tRNA)TrmKX-ray crystallography

Identifiers

PMID35595101
PMCPMC9190014
OpenAlexW4280501877

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.