Evidence map›Paper›PMID 35595012›Full record

ReviewDrug discovery today2022

Selection of data sets for FAIRification in drug discovery and development: Which, why, and how?

Ebtisam Alharbi, Yojana Gadiya, David Henderson, Andrea Zaliani, Alejandra Delfin-Rossaro, Anne Cambon-Thomsen, Manfred Kohler, Gesa Witt, Danielle Welter, Nick Juty and 8 more

Abstract readReview
In one paragraph

Review in Drug discovery today, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Ebtisam AlharbiDepartment of Computer Science, The University of Manchester, Oxford Road, Manchester, UK; College of Computer and Information Systems, Umm Al-Qura University, Mecca, Saudi Arabia.
Yojana GadiyaFraunhofer Institute for Translational Medicine and Pharmacology (ITMP), Schnackenburgallee 114, 22525 Hamburg, and Theodor Stern Kai 7, 60590 Frankfurt, Germany; Fraunhofer Cluster of Excellence for Immune Mediated Diseases (CIMD), Theodor Stern Kai 7, 60590 Frankfurt, Germany.
David HendersonBayer AG, Research & Development, Pharmaceuticals, Müllerstrasse 178, 13353 Berlin, Germany.
Andrea ZalianiFraunhofer Institute for Translational Medicine and Pharmacology (ITMP), Schnackenburgallee 114, 22525 Hamburg, and Theodor Stern Kai 7, 60590 Frankfurt, Germany; Fraunhofer Cluster of Excellence for Immune Mediated Diseases (CIMD), Theodor Stern Kai 7, 60590 Frankfurt, Germany.
Alejandra Delfin-RossaroCERPOP, UMR 1295, INSERM, Université Paul Sabatier -Toulouse III, France.
Anne Cambon-ThomsenCERPOP, UMR 1295, INSERM, Université Paul Sabatier -Toulouse III, France.
Manfred KohlerFraunhofer Institute for Translational Medicine and Pharmacology (ITMP), Schnackenburgallee 114, 22525 Hamburg, and Theodor Stern Kai 7, 60590 Frankfurt, Germany; Fraunhofer Cluster of Excellence for Immune Mediated Diseases (CIMD), Theodor Stern Kai 7, 60590 Frankfurt, Germany.
Gesa WittFraunhofer Institute for Translational Medicine and Pharmacology (ITMP), Schnackenburgallee 114, 22525 Hamburg, and Theodor Stern Kai 7, 60590 Frankfurt, Germany; Fraunhofer Cluster of Excellence for Immune Mediated Diseases (CIMD), Theodor Stern Kai 7, 60590 Frankfurt, Germany.
Danielle WelterLuxembourg Centre for Systems Biomedicine, ELIXIR Luxembourg, University of Luxembourg, L-4367 Belval, Luxembourg.
Nick JutyDepartment of Computer Science, The University of Manchester, Oxford Road, Manchester, UK.
Caroline JayDepartment of Computer Science, The University of Manchester, Oxford Road, Manchester, UK.
Ola EngkvistDiscovery Sciences, R&D, AstraZeneca, SE-43183 Mölndal, Sweden.
Carole GobleDepartment of Computer Science, The University of Manchester, Oxford Road, Manchester, UK.
Dorothy S ReillyNovartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Switzerland.
Venkata SatagopamLuxembourg Centre for Systems Biomedicine, ELIXIR Luxembourg, University of Luxembourg, L-4367 Belval, Luxembourg.
Vassilios IoannidisSIB Swiss Institute of Bioinformatics, Quartier Sorge - Batiment Amphipole, 1015 Lausanne, Switzerland. Electronic address: Vassilios.Ioannidis@sib.swiss.
Wei GuLuxembourg Centre for Systems Biomedicine, ELIXIR Luxembourg, University of Luxembourg, L-4367 Belval, Luxembourg. Electronic address: Wei.Gu@uni.lu.
Philip GribbonFraunhofer Institute for Translational Medicine and Pharmacology (ITMP), Schnackenburgallee 114, 22525 Hamburg, and Theodor Stern Kai 7, 60590 Frankfurt, Germany; Fraunhofer Cluster of Excellence for Immune Mediated Diseases (CIMD), Theodor Stern Kai 7, 60590 Frankfurt, Germany. Electronic address: Philip.Gribbon@itmp.fraunhofer.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the intuitive value of adopting the Findable, Accessible, Interoperable, and Reusable (FAIR) principles in both academic and industrial sectors, challenges exist in resourcing, balancing long- versus short-term priorities, and achieving technical implementation. This situation is exacerbated by the unclear mechanisms by which costs and benefits can be assessed when decisions on FAIR are made. Scientific and research and development (R&D) leadership need reliable evidence of the potential benefits and information on effective implementation mechanisms and remediating strategies. In this article, we describe procedures for cost-benefit evaluation, and identify best-practice approaches to support the decision-making process involved in FAIR implementation.

Indexed as

Drug DiscoveryCost-Benefit AnalysisCost–benefitDrug discoveryFAIRFAIRificationPharmaceutical R&D

Identifiers

PMID35595012
PMCPMC9236643

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.