Evidence map›Paper›PMID 35594972›Full record

ArticleJournal of affective disorders2022

App-enhanced transdiagnostic CBT for adolescents with mood or psychotic spectrum disorders.

Marc J Weintraub, Megan C Ichinose, Jamie Zinberg, Monica Done, Georga M Morgan-Fleming, Catherine A Wilkerson, Robin D Brown, Carrie E Bearden, David J Miklowitz

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of affective disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. A Systematic Review of Mobile Apps as an Adjunct to Psychological Interventions for Emotion Dysregulation.International journal of environmental research and public health · 2023
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marc J WeintraubSemel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, USA. Electronic address: mjweintraub@mednet.ucla.edu.
Megan C IchinoseSemel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, USA.
Jamie ZinbergSemel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, USA.
Monica DoneSemel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, USA.
Georga M Morgan-FlemingSemel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, USA.
Catherine A WilkersonSemel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, USA.
Robin D BrownSemel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, USA.
Carrie E BeardenSemel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, USA; Department of Psychology, University of California, Los Angeles, CA, USA.
David J MiklowitzSemel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, USA; Department of Psychology, University of California, Los Angeles, CA, USA.

Funding

Family-Focused Therapy for Individuals at High Clinical Risk for Psychosis: A Confirmatory Efficacy TrialR01MH123575 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BEARDEN, CARRIE E, MIKLOWITZ, DAVID JAY · 2020 to 2023
$5.4M
Neurodevelopment and Psychosis in the 22q11.2 Copy Number VariantsR37MH085953 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CARRIE E BEARDEN · 2023 to 2026
$2.9M
Technology-Enhanced Family-Focused Treatment for Adolescents at High Risk for Mood DisordersR34MH117200 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI AREVIAN, ARMEN C, MIKLOWITZ, DAVID JAY · 2018 to 2020
$933k
App-Enhanced CBT for Adolescents at High Risk for Severe Mood DisordersK23MH124015 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WEINTRAUB, MARC JOSHUA · 2021 to 2024
$779k
NIMH NIH HHS K23 MH124015NIMH NIH HHS R01 MH123575NIMH NIH HHS R34 MH117200NIMH NIH HHS R37 MH085953
6 · The paper itself

Abstract

backgroundAlthough transdiagnostic forms of cognitive-behavioral therapy (CBT) have been evaluated in individuals with depressive and anxiety disorders, few studies have examined their suitability for more severe disorders, such as recurrent or persistent major depressive disorder, bipolar disorder, or psychotic spectrum disorders. This study examined the acceptability and initial efficacy of an app-enhanced Unified Protocol for Adolescents [UP-A] when including youth with more severe mood disorders or psychotic spectrum disorders.

methodsWe first adapted a mobile application (app), based on user-centered feedback from adolescents and their parents, to assist participants in reviewing session content, practicing skills learned in previous treatment sessions, and monitoring symptomatic progress. A total of 24 adolescents (M age = 15.2 years, SD = 1.6) with mood or psychotic spectrum disorders and their parents then participated in an open trial of the app-enhanced group treatment given over 9 weekly sessions.

resultsAdolescent participants and their parents rated the group treatment and mobile app as acceptable and useful. We observed significant improvements over the 9-week treatment in adolescents' depressive symptoms, attenuated psychotic symptoms, and global functioning. The frequency with which adolescents used the mobile app between sessions was positively related to symptomatic and functional gains.

conclusionsInitial findings suggest the acceptability and feasibility of a mobile app that enabled adolescent participants and their parents to review session content and practice treatment skills. Findings also indicated improvements in psychiatric and functional outcomes among the adolescent participants over the course of the app-enhanced treatment. Randomized clinical trials are needed to evaluate the efficacy of app-enhanced CBT in improving symptoms and functioning in adolescents with mood or psychotic spectrum disorders.

Indexed as

Cognitive Behavioral TherapyMajor Depressive DisorderMobile ApplicationsPsychotic DisordersAdolescentAnxiety DisordersHumansbipolarclinical high riskcognitive behavioral therapydepressionmHealthpsychosisUnified Protocolunipolaryouth

Identifiers

PMID35594972
PMCPMC9728252

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.