Evidence map›Paper›PMID 35594831›Full record

Observational studyJournal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia2022

Seizures and COVID-19: Results from the Spanish Society of Neurology's COVID-19 registry.

Santiago Fernández Fernández, Javier Ricardo Pérez Sánchez, Guillermo Hernández Pérez, María Rabasa Pérez, Cristina Guijarro Castro, David García-Azorín, David Ezpeleta

Abstract readObservational Study
In one paragraph

Observational study in Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. A Unique Case of COVID-19 Presenting as Focal Seizures With Impaired Awareness.Journal of investigative medicine high impact case reports
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Santiago Fernández FernándezHospital Clínic de Barcelona, Calle Plató, 21, 08006 Barcelona, Spain.
Javier Ricardo Pérez SánchezHospital General Universitario Gregorio Marañón, Calle del Doctor Esquerdo, 46, 28007 Madrid, Spain.
Guillermo Hernández PérezHospitalUniversitari de Bellvitge, L' Hospitalet de Llobregat, C/ de la FeixaLlarga, s/n, 08907 Hospitalet de Llobregat, Barcelona, Spain.
María Rabasa PérezHospital Universitario de Fuenlabrada, Camino del Molino, 2, 28942 Fuenlabrada, Madrid, Spain.
Cristina Guijarro CastroHospital Universitario HM Puerta del Sur, Avda. de Carlos V, 70, 28938 Móstoles, Madrid, Spain.
David García-AzorínHospital Clínico Universitario, Paseo de Zorrilla, 1, 47007 Valladolid, Spain.
David EzpeletaHospital Universitario Quirónsalud Madrid, Pozuelo de Alarcón, c/ Diego de Velázquez, 1, 28223 Pozuelo de Alarcón, Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describea series of patients with COVID-19 who presented with seizures, reported in the Spanish Society of Neurology's COVID-19 Registry. This observational, descriptive,multicentre, registry-based study includes patients with confirmed COVID-19 who experienced seizures during active infection.Wedescribe theclinicalpresentation of COVID-19,seizures,and resultsof complementary tests.Wealsodescribe the suspectedaetiologyof the seizures. Of 232 reported cases, 26 (11.2%) presented with seizures;7 of these patients (26.9%) had prior history of epilepsy, whereas the remaining 19 (73.1%) had no history of seizures.In most cases, seizures presented on days 0 and 7 after onset of COVID-19. By seizure type, 8 patients (30.7%) presentedgeneralised tonic-clonic seizures, 7 (26.9%) status epilepticus, 8 (30.7%) focal impaired-awareness seizures, and 4 (11.7%) secondary generalised seizures.Six patients (23.1%) also presented other neurological symptoms, includingaltered mental status and decreased level of consciousness. Predisposing factors for seizures (eg, dementia, tumour, cerebrovascular disease) were observed in 10 of the 19 patients with no prior history of epilepsy (52.6%). Patients with COVID-19 may present with seizures over the course of the disease,either alone or in the context of encephalopathy.Seizures may present in patients with no prior history of epilepsy; however, most of these patients present predisposing factors.

Indexed as

COVID-19EpilepsyEpilepsy, Tonic-ClonicNeurologyAnticonvulsantsElectroencephalographyHumansRegistriesSeizuresAnticonvulsantsAcute symptomatic seizuresCOVID-19EncephalopathyEpilepsySeizures

Identifiers

PMID35594831
PMCPMC9108087

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.