Evidence map›Paper›PMID 35594552›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2023

Reduced Odds of Severe Acute Respiratory Syndrome Coronavirus 2 Reinfection After Vaccination Among New York City Adults, July 2021-November 2021.

Alison Levin-Rector, Lauren Firestein, Emily McGibbon, Jessica Sell, Sungwoo Lim, Ellen H Lee, Don Weiss, Anita Geevarughese, Jane R Zucker, Sharon K Greene

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Alison Levin-RectorBureau of Communicable Disease, New York City Department of Health and Mental Hygiene, Long Island City, New York, USA.
Lauren FiresteinBureau of Communicable Disease, New York City Department of Health and Mental Hygiene, Long Island City, New York, USA.
Emily McGibbonBureau of Communicable Disease, New York City Department of Health and Mental Hygiene, Long Island City, New York, USA.
Jessica SellBureau of Communicable Disease, New York City Department of Health and Mental Hygiene, Long Island City, New York, USA.
Sungwoo LimBureau of Epidemiology Services, New York City Department of Health and Mental Hygiene, Long Island City, New York, USA.
Ellen H LeeBureau of Communicable Disease, New York City Department of Health and Mental Hygiene, Long Island City, New York, USA.
Don WeissBureau of Communicable Disease, New York City Department of Health and Mental Hygiene, Long Island City, New York, USA.
Anita GeevarugheseBureau of Public Health Training and Information Dissemination, New York City Department of Health and Mental Hygiene, Long Island City, New York, USA.
Jane R ZuckerBureau of Immunization, New York City Department of Health and Mental Hygiene, Long Island City, New York, USA.
Sharon K GreeneBureau of Communicable Disease, New York City Department of Health and Mental Hygiene, Long Island City, New York, USA.
New York City Department of Health and Mental Hygiene · US

Funding

CDC
6 · The paper itself

Abstract

backgroundBelief that vaccination is not needed for individuals with prior infection contributes to coronavirus disease 2019 (COVID-19) vaccine hesitancy. Among individuals infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) before vaccines became available, we determined whether vaccinated individuals had reduced odds of reinfection.

methodsWe conducted a case-control study among adult New York City residents who tested positive for SARS-CoV-2 infection in 2020 and had not died or tested positive again >90 days after an initial positive test as of 1 July 2021. Case patients with reinfection during July 2021-November 2021 and controls with no reinfection were matched (1:3) on age, sex, timing of initial positive test in 2020, and neighborhood poverty level. Matched odds ratios (mORs) and 95% confidence intervals (CIs) were calculated using conditional logistic regression.

resultsOf 349 827 eligible adults, 2583 were reinfected during July 2021-November 2021. Of 2401 with complete matching criteria data, 1102 (45.9%) were known to be symptomatic for COVID-19-like illness, and 96 (4.0%) were hospitalized. Unvaccinated individuals, compared with individuals fully vaccinated within the prior 90 days, had elevated odds of reinfection (mOR, 3.21; 95% CI, 2.70 to 3.82), of symptomatic reinfection (mOR, 2.97; 95% CI, 2.31 to 3.83), and of reinfection with hospitalization (mOR, 2.09; 95% CI, .91 to 4.79).

conclusionsVaccination reduced odds of reinfections when the Delta variant predominated. Further studies should assess risk of severe outcomes among reinfected persons as new variants emerge, infection- and vaccine-induced immunity wanes, and booster doses are administered.

Indexed as

COVID-19SARS-CoV-2AdultCase-Control StudiesCOVID-19 VaccinesHumansNew York CityReinfectionVaccinationCOVID-19 VaccinesCOVID-19Delta variantreinfectionSARS-CoV-2vaccination

Identifiers

PMID35594552
PMCPMC9129172
OpenAlexW4281262135

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.