Evidence map›Paper›PMID 35594505›Full record

ArticleJCO oncology practice2022

Long-Term Health-Related Quality of Life of Autologous Hematopoietic Cell Transplantation Patients and Nontransplant Patients With Aggressive Lymphoma: A Prospective Cohort Analysis.

Christopher S Strouse, Melissa C Larson, Shawna L Ehlers, Kathleen J Yost, Matthew J Maurer, Stephen M Ansell, David J Inwards, Patrick B Johnston, Ivana N Micallef, Brian K Link and 3 more

Open access · greenAbstract read
In one paragraph

Article in JCO oncology practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Patient-Reported Outcome Measures (PROMS) in Lymphoma.Current oncology (Toronto, Ont.) · 2025
    Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Christopher S StrouseDivision of Hematology, Oncology, and Blood and Marrow Transplantation, University of Iowa, Iowa City, IA.ORCID 0000-0003-4964-167X
Melissa C LarsonDepartment of Health Sciences Research, Mayo Clinic, Rochester, MN.
Shawna L EhlersDepartment of Psychiatry and Psychology, Mayo Clinic, Rochester, MN.
Kathleen J YostDepartment of Health Sciences Research, Mayo Clinic, Rochester, MN.ORCID 0000-0002-9641-5627
Matthew J MaurerDepartment of Health Sciences Research, Mayo Clinic, Rochester, MN.ORCID 0000-0002-1867-0526
Stephen M AnsellDepartment of Internal Medicine, Division of Hematology, Mayo Clinic, Rochester, MN.ORCID 0000-0003-1244-6758
David J InwardsDepartment of Internal Medicine, Division of Hematology, Mayo Clinic, Rochester, MN.
Patrick B JohnstonDepartment of Internal Medicine, Division of Hematology, Mayo Clinic, Rochester, MN.
Ivana N MicallefDepartment of Internal Medicine, Division of Hematology, Mayo Clinic, Rochester, MN.ORCID 0000-0002-4675-4903
Brian K LinkDivision of Hematology, Oncology, and Blood and Marrow Transplantation, University of Iowa, Iowa City, IA.ORCID 0000-0001-5084-0698
Umar FarooqDivision of Hematology, Oncology, and Blood and Marrow Transplantation, University of Iowa, Iowa City, IA.ORCID 0000-0001-7891-9891
James R CerhanDepartment of Health Sciences Research, Mayo Clinic, Rochester, MN.ORCID 0000-0002-7482-178X
Carrie A ThompsonDepartment of Internal Medicine, Division of Hematology, Mayo Clinic, Rochester, MN.ORCID 0000-0002-4518-2309
Mayo Clinic in Arizona · USMayo Clinic in Florida · USUniversity of Iowa · US

Funding

Women's Cancer ProgramP30CA015083 · NCI · MAYO CLINIC ROCHESTER · PI Felicity Enders · 1985 to 2026
$151.3M
Viral VectorP30CA086862 · NCI · UNIVERSITY OF IOWA · PI Douglas Robert Spitz · 2000 to 2026
$70.0M
The Role of Monocytes in non-Hodgkin LymphomaP50CA097274 · NCI · UNIVERSITY OF IOWA · PI WEINER, GEORGE J. · 2002 to 2021
$45.7M
The Lymphoma Epidemiology of Outcomes (LEO) Cohort Study (Supplement)U01CA195568 · NCI · MAYO CLINIC ROCHESTER · PI CERHAN, JAMES R, FLOWERS, CHRISTOPHER R · 2015 to 2025
$22.1M
PROGRAM IN HEMOSTASIS AND THROMBOSIS FOR ACADEMICT32HL007344 · NHLBI · UNIVERSITY OF IOWA · PI Anil Kumar Chauhan, Steven R Lentz · 1985 to 2026
$6.5M
NCI NIH HHS P30 CA015083NCI NIH HHS U01 CA195568NHLBI NIH HHS T32 HL007344
6 · The paper itself

Abstract

purposeThis study assessed the long-term quality of life (QOL) of patients with aggressive lymphoma subtypes treated with autologous hematopoietic cell transplant (autoHCT) compared with those without history of transplant.

methodsPatient-reported QOL measures were prospectively gathered from patients enrolled in the Iowa/Mayo Specialized Program of Research Excellence Molecular Epidemiology Resource cohort with aggressive lymphoma subtypes. QOL was measured using the Functional Assessment of Cancer Therapy-General (FACT-G), Functional Assessment of Chronic Illness Therapy-Fatigue Scale, State-Trait Anxiety Inventory (STAI), and Profile of Mood States instruments and with a numeric rating scale for overall QOL and spiritual QOL. The autoHCT group and no HCT groups were compared at 3 years (FU3) and 6 years (FU6) after lymphoma diagnosis.

resultsIn total, 980 patients with lymphoma (106 autoHCT and 874 no HCT) diagnosed between 2002 and 2013 were included for analysis. The mean FACT-G total score was similar in the autoHCT and no HCT groups at FU3 (89.9

conclusionPatients remaining in remission at 3 and 6 years after diagnosis had a high level of QOL with no significant differences associated with history of treatment with autoHCT.

Indexed as

Hematopoietic Stem Cell TransplantationLymphomaCohort StudiesHumansProspective StudiesQuality of Life

Identifiers

PMID35594505
PMCPMC9287288
OpenAlexW4280567686

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.