Evidence map›Paper›PMID 35594344›Full record

ArticleScience advances2022

Absence of structural brain changes from mindfulness-based stress reduction: Two combined randomized controlled trials.

Tammi R A Kral, Kaley Davis, Cole Korponay, Matthew J Hirshberg, Rachel Hoel, Lawrence Y Tello, Robin I Goldman, Melissa A Rosenkranz, Antoine Lutz, Richard J Davidson

Registry-linked trialAbstract read
In one paragraph

Article in Science advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07544355 (A Mindfulness-Based Stress Reduction Training Program Model for Empowering Nursing Students), which is not on this map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07544355 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

A Mindfulness-Based Stress Reduction Training Program Model for Empowering Nursing Students

TypeinterventionalSponsorIstanbul Medeniyet UniversityRan2026 to 2027Enrolled93ConditionsDepression, Anxiety, Stress, Well-Being, PsychologicalArmsThe mindfulness group-"Mindfulness-Based Stress Reduction Program", The life skills workshop group-"Lifestyle Management and Well-being Workshop"
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Trial
  6. A randomized controlled trial of a 14-day mindfulness ecological momentary intervention (MEMI) for generalized anxiety disorder.European psychiatry : the journal of the Association of European Psychiatrists · 2023
    Trial
  7. Review
  8. Review
  9. Review
  10. Article
  11. ENIGMA-Meditation: Worldwide Consortium for Neuroscientific Investigations of Meditation Practices.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2025
    Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Observational
  17. Re-examining the Mysterious Role of the Cerebellum in Pain.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tammi R A KralCenter for Healthy Minds, University of Wisconsin-Madison, Madison, WI, USA.ORCID 0000-0002-0999-1424
Kaley DavisCenter for Healthy Minds, University of Wisconsin-Madison, Madison, WI, USA.
Cole KorponayCenter for Healthy Minds, University of Wisconsin-Madison, Madison, WI, USA.
Matthew J HirshbergCenter for Healthy Minds, University of Wisconsin-Madison, Madison, WI, USA.
Rachel HoelCenter for Healthy Minds, University of Wisconsin-Madison, Madison, WI, USA.ORCID 0000-0001-9195-0316
Lawrence Y TelloCenter for Healthy Minds, University of Wisconsin-Madison, Madison, WI, USA.
Robin I GoldmanCenter for Healthy Minds, University of Wisconsin-Madison, Madison, WI, USA.ORCID 0000-0002-4957-2486
Melissa A RosenkranzCenter for Healthy Minds, University of Wisconsin-Madison, Madison, WI, USA.ORCID 0000-0001-8432-9011
Antoine LutzWaisman Laboratory for Brain Imaging and Behavior, University of Wisconsin-Madison, Madison, WI, USA.ORCID 0000-0002-0258-3233
Richard J DavidsonCenter for Healthy Minds, University of Wisconsin-Madison, Madison, WI, USA.ORCID 0000-0002-8506-4964

Funding

WISCONSIN CENTER ON MENTAL RETARDATION: CORE SUPPORTP30HD003352 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI DAVIDSON, RICHARD J · 1985 to 2015
$25.2M
Wisconsin Center for the Neuroscience and Psychophysiology of MeditationP01AT004952 · NCCIH · UNIVERSITY OF WISCONSIN-MADISON · PI DAVIDSON, RICHARD J · 2008 to 2018
$14.7M
TRAINING PROGRAM IN EMOTION RESEARCHT32MH018931 · NIMH · UNIVERSITY OF WISCONSIN-MADISON · PI Richard J Davidson · 1989 to 2026
$11.6M
STRESS EXPOSURE, HPA ACTIVITY AND RISK FOR ADOLESCENT INTERNALIZING DISORDERSP50MH084051 · NIMH · UNIVERSITY OF WISCONSIN-MADISON · PI ALEXANDER, ANDREW L · 2008 to 2012
$9.6M
Neural Substrates of Affective Style and Emotion RegulationR01MH043454 · NIMH · UNIVERSITY OF WISCONSIN-MADISON · PI DAVIDSON, RICHARD J, SCHAEFER, STACEY M · 1989 to 2022
$9.6M
Waisman Intellectual and Developmental Disabilities Research Center Down Syndrome RegistryU54HD090256 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI DAVIDSON, RICHARD J · 2016 to 2020
$6.0M
The plasticity of well-being: A research network to define, measure and promote human flourishingU24AT011289 · NCCIH · UNIVERSITY OF WISCONSIN-MADISON · PI DAVIDSON, RICHARD J · 2021 to 2024
$2.4M
NCCIH NIH HHS P01 AT004952NCCIH NIH HHS U24 AT011289NICHD NIH HHS P30 HD003352NICHD NIH HHS U54 HD090256NIMH NIH HHS P50 MH084051NIMH NIH HHS R01 MH043454NIMH NIH HHS T32 MH018931
6 · The paper itself

Abstract

Studies purporting to show changes in brain structure following the popular, 8-week mindfulness-based stress reduction (MBSR) course are widely referenced despite major methodological limitations. Here, we present findings from a large, combined dataset of two, three-arm randomized controlled trials with active and waitlist (WL) control groups. Meditation-naïve participants (

Identifiers

PMID35594344
PMCPMC9122316

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.