ArticleAnnals of medicine2022
Correlation between dietary selenium intake and stroke in the National Health and Nutrition Examination Survey 2003-2018.
Article in Annals of medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Selenium nutritional status and cardiovascular diseases: mechanisms of cardioprotection and 21 years of global research trends in precision prevention (2005-2026).Frontiers in nutrition · 2026Pooled it
- Dietary zinc intake associated with stroke in American adults.Scientific reports · 2025Article
- Association between dietary selenium intake and the risk of cardiovascular disease in US adults: a population-based study.Scientific reports · 2025Article
- Genetically Elevated Selenoprotein S Levels and Risk of Stroke: A Two-Sample Mendelian Randomization Analysis.International journal of molecular sciences · 2025Article
- Relationship between selenium intake, circulating selenium levels, and stroke: a systematic review and meta-analysis.Frontiers in neurology · 2025Review
- Association between dietary selenium intake and depression in patients with or without stroke: a cross-sectional study.Frontiers in nutrition · 2025Article
- Aripiprazole once-monthly for the treatment of adult patients with earlier-stage bipolar I disorder: a post hoc analysis of data from a double-blind, placebo-controlled, 52-week randomized withdrawal trial.International journal of bipolar disorders · 2024Article
- Association between the Composite Dietary Antioxidant Index and Stroke: A cross-sectional Study.Biological trace element research · 2024Article
- Effect of dietary selenium intake on CVD: a retrospective cohort study based on China Health and Nutrition Survey (CHNS) data.Public health nutrition · 2024Article
- Association between dietary selenium intake and the prevalence of hypertension: results from the National Health and Nutrition Examination Survey 2003-2018.Frontiers in immunology · 2024Article
- Research trends in nutritional interventions for stroke: a bibliometric analysis and literature review.Frontiers in nutrition · 2024Article
- Inhibition of hyperpolarization-activated cyclic nucleotide-gated cation channel attenuates cerebral ischemia reperfusion-induced impairment of learning and memory by regulating apoptotic pathway.Metabolic brain disease · 2023Article
- Selenium supplementation provides potent neuroprotection following cerebral ischemia in mice.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023Article
- Association between selenium intake and migraine: a nationwide cross-sectional study.Frontiers in neuroscience · 2023Article
- Associations between homocysteine and B vitamins and stroke: a cross-sectional study.Frontiers in neurology · 2023Article
- Higher oxidative balance score decreases risk of stroke in US adults: evidence from a cross-sectional study.Frontiers in cardiovascular medicine · 2023Article
- Selenium substituted axitinib reduces axitinib side effects and maintains its anti-renal tumor activity.RSC advances · 2022Article
- Association of habitually low intake of dietary selenium with new-onset stroke: A retrospective cohort study (2004-2015 China Health and Nutrition Survey).Frontiers in public health · 2022Article
- Association of obesity with headache among US children and adolescents: Evidence from NHANES 1999-2004.Frontiers in endocrinology · 2022Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEpidemiologic evidence of the effect of dietary selenium intake on stroke risk remains controversial. This study aimed to examine the cross-sectional correlation between dietary selenium intake and the risk of stroke in adults. MATERIALS AND
methodsWe retrospectively analysed 39,438 participants from the National Health and Nutrition Examination Survey 2003-2018, aged 20-85 years. Participants were divided into quartiles depending on daily dietary selenium intake: quartile 1 (0-77 μg), quartile 2 (77-108 μg), quartile 3 (108-148 μg), and quartile 4 (148-400 μg). The dose-response relationship was assessed using the restricted cubic spline function.
resultsThe adjusted odds ratios (ORs) and 95% confidence intervals (CIs) of stroke were 0.70 (0.55, 0.88) for participants in quartile 2, 0.71 (0.53, 0.93) for quartile 3, and 0.61 (0.43, 0.85) for quartile 4 compared with that in quartile 1.
conclusionsDietary selenium had a negative and non-linear correlation with the risk of stroke in adults. The correlation varied across different population subgroups.KEY MESSAGESDietary selenium had a negative and non-linear correlation with the risk of stroke in adults.Non-linear negative correlation trends were observed in subpopulations of females, age <60 years, poverty-income ratio <2.14, overweight and obesity, hypertension, non-diabetes, and non-anaemia.Dietary selenium intake of approximately 105 μg per day has an optimum effect on stroke.
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