Evidence map›Paper›PMID 35594182›Full record

ArticleMolecular biology of the cell2022

Acentrosomal spindle assembly and maintenance in

Ian D Wolff, Jeremy A Hollis, Sarah M Wignall

Open access · greenAbstract read
In one paragraph

Article in Molecular biology of the cell, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Ian D WolffDepartment of Molecular Biosciences, Northwestern University, Evanston, IL 60208.
Jeremy A HollisDepartment of Molecular Biosciences, Northwestern University, Evanston, IL 60208.
Sarah M WignallDepartment of Molecular Biosciences, Northwestern University, Evanston, IL 60208.
Northwestern University · US

Funding

Molecular Biophysics Training Program at Northwestern UniversityT32GM008382 · NIGMS · NORTHWESTERN UNIVERSITY · PI RADHAKRISHNAN, ISHWAR · 1990 to 2020
$4.3M
Regulation of chromosome segregation during oocyte meiosisR01GM124354 · NIGMS · NORTHWESTERN UNIVERSITY · PI SARAH Marie WIGNALL · 2018 to 2026
$2.8M
NIGMS NIH HHS R01 GM124354NIGMS NIH HHS T32 GM008382
6 · The paper itself

Abstract

During the meiotic divisions in oocytes, microtubules are sorted and organized by motor proteins to generate a bipolar spindle in the absence of centrosomes. In most organisms, kinesin-5 family members crosslink and slide microtubules to generate outward force that promotes acentrosomal spindle bipolarity. However, the mechanistic basis for how other kinesin families act on acentrosomal spindles has not been explored. We investigated this question in

Indexed as

Caenorhabditis elegans ProteinsKinesinsAnimalsCaenorhabditis elegansMeiosisMicrotubulesOocytesSpindle ApparatusCaenorhabditis elegans ProteinsKinesinsKLP-18 protein, C elegans

Identifiers

PMID35594182
PMCPMC9635285
OpenAlexW4281257187

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.