Evidence map›Paper›PMID 35593967›Full record

Observational studyInternal and emergency medicine2022

Clinical impact of vital sign abnormalities in patients admitted with acute exacerbation of chronic obstructive pulmonary disease: an observational study using continuous wireless monitoring.

Mikkel Elvekjaer, Søren M Rasmussen, Katja K Grønbæk, Celeste M Porsbjerg, Jens-Ulrik Jensen, Camilla Haahr-Raunkjær, Jesper Mølgaard, Marlene Søgaard, Helge B D Sørensen, Eske K Aasvang and 1 more

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Internal and emergency medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Mikkel ElvekjaerDepartment of Anaesthesia and Intensive Care, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Bispebjerg Bakke 23, 2400, Copenhagen, NV, Denmark. mikkelelvekjaer@gmail.com.ORCID 0000-0003-3601-8432
Søren M RasmussenBiomedical Engineering, Department of Health Technology, Technical University of Denmark, Kgs. Lyngby, Denmark.ORCID 0000-0002-6297-2871
Katja K GrønbækDepartment of Anaesthesia and Intensive Care, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Bispebjerg Bakke 23, 2400, Copenhagen, NV, Denmark.ORCID 0000-0003-3045-6909
Celeste M PorsbjergCopenhagen Center for Translational Research, Bispebjerg and Frederiksberg, Copenhagen University Hospital, Copenhagen, Denmark.ORCID 0000-0003-4825-9436
Jens-Ulrik JensenDepartment of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0003-4036-0521
Camilla Haahr-RaunkjærDepartment of Anaesthesia and Intensive Care, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Bispebjerg Bakke 23, 2400, Copenhagen, NV, Denmark.ORCID 0000-0001-8646-5666
Jesper MølgaardDepartment of Anaesthesia and Intensive Care, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Bispebjerg Bakke 23, 2400, Copenhagen, NV, Denmark.ORCID 0000-0003-2062-9570
Marlene SøgaardDepartment of Anaesthesia and Intensive Care, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Bispebjerg Bakke 23, 2400, Copenhagen, NV, Denmark.
Helge B D Sørensen *Biomedical Engineering, Department of Health Technology, Technical University of Denmark, Kgs. Lyngby, Denmark.
Eske K Aasvang *Department of Anaesthesiology, Centre for Cancer and Organ Dysfunction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-7131-2461
Christian S Meyhoff *Department of Anaesthesia and Intensive Care, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Bispebjerg Bakke 23, 2400, Copenhagen, NV, Denmark.ORCID 0000-0002-4885-4609
University of Copenhagen · DKTechnical University of Denmark · DK

Funding

Innovationsfonden 8056-00055BKræftens Bekæmpelse R150-A9865-16-S48
6 · The paper itself

Abstract

Early detection of abnormal vital signs is critical for timely management of acute hospitalised patients and continuous monitoring may improve this. We aimed to assess the association between preceding vital sign abnormalities and serious adverse events (SAE) in patients hospitalised with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Two hundred patients' vital signs were wirelessly and continuously monitored with peripheral oxygen saturation, heart rate, and respiratory rate during the first 4 days after admission for AECOPD. Non-invasive blood pressure was also measured every 30-60 min. The primary outcome was occurrence of SAE according to international definitions within 30 days and physiological data were analysed for preceding vital sign abnormalities. Data were presented as the mean cumulative duration of vital sign abnormalities per 24 h and analysed using Wilcoxon rank sum test. SAE during ongoing continuous monitoring occurred in 50 patients (25%). Patients suffering SAE during the monitoring period had on average 455 min (SD 413) per 24 h of any preceding vital sign abnormality versus 292 min (SD 246) in patients without SAE, p = 0.08, mean difference 163 min [95% CI 61-265]. Mean duration of bradypnea (respiratory rate < 11 min

Indexed as

Pulmonary Disease, Chronic ObstructiveHospitalizationHumansMonitoring, PhysiologicRespiratory RateVital SignsAcute exacerbation of chronic obstructive pulmonary diseaseClinical deteriorationMonitoringOutcomeVital signs/physiologyWireless technology

Identifiers

PMID35593967
OpenAlexW4280523084

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.