Evidence map›Paper›PMID 35593878›Full record

ReviewASAIO journal (American Society for Artificial Internal Organs : 1992)2022

Analgosedation in Critically Ill Adults Receiving Extracorporeal Membrane Oxygenation Support.

Jessica Crow, John Lindsley, Sung-Min Cho, Jing Wang, James H Lantry, Bo S Kim, Pouya Tahsili-Fahadan

Open access · greenAbstract readReview
In one paragraph

Review in ASAIO journal (American Society for Artificial Internal Organs : 1992), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Guideline
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  9. Immediate post-ECPR management strategies in the prehospital and critical care transport medicine environments.Scandinavian journal of trauma, resuscitation and emergency medicine · 2025
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Jessica CrowFrom the Department of Pharmacy, Johns Hopkins Hospital, Baltimore, Maryland.
John LindsleyFrom the Department of Pharmacy, Johns Hopkins Hospital, Baltimore, Maryland.
Sung-Min ChoNeurocritical Care Division, Departments of Neurology, Neurosurgery, and Anesthesiology & Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Jing WangMedical Critical Care Service, Department of Medicine, Inova Fairfax Medical Campus, Falls Church, Virginia.
James H LantryMedical Critical Care Service, Department of Medicine, Inova Fairfax Medical Campus, Falls Church, Virginia.
Bo S KimDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Pouya Tahsili-FahadanNeurocritical Care Division, Departments of Neurology, Neurosurgery, and Anesthesiology & Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Inova Fairfax Hospital · USJohns Hopkins Hospital · USJohns Hopkins Medicine · USJohns Hopkins University · US

Funding

CLots and Oxygen in Va-ExtracorpoReal membrane oxygenation (CLOVER) studyK23HL157610 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI Sung-Min Cho · 2022 to 2026
$797k
NHLBI NIH HHS K23 HL157610
6 · The paper itself

Abstract

Extracorporeal membrane oxygenation (ECMO) is an increasingly utilized intervention for cardiopulmonary failure. Analgosedation during ECMO support is essential to ensure adequate pain and agitation control and ventilator synchrony, optimize ECMO support, facilitate patient assessment, and minimize adverse events. Although the principles of analgosedation are likely similar for all critically ill patients, ECMO circuitry alters medication pharmacodynamics and pharmacokinetics. The lack of clinical guidelines for analgosedation during ECMO, especially at times of medication shortage, can affect patient management. Here, we review pharmacological considerations, protocols, and special considerations for analgosedation in critically ill adults receiving ECMO support.

Indexed as

Extracorporeal Membrane OxygenationAdultCritical IllnessHumans

Identifiers

PMID35593878
PMCPMC9675878
OpenAlexW4281258565

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.