ArticleBrain and behavior2022
Cognitive function in patients with neuroborreliosis: A prospective cohort study from the acute phase to 12 months post treatment.
Article in Brain and behavior, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Treatment of post-treatment Lyme disease symptoms-a systematic review.European journal of neurology · 2024Pooled it
- Residual Symptoms and Quality of Life After Treated Lyme Neuroborreliosis: Case-Control Study (QoLYME).Open forum infectious diseases · 2025Article
- Are white matter hyperintensities associated with neuroborreliosis? The answer is twofold.Neuroradiology · 2025Article
- Neuropsychiatric Manifestations of Lyme Disease: A Literature Review of Psychiatric and Cognitive Impacts.Acta medica Lituanic · 2025Article
- Dynamic contrast-enhanced MRI shows altered blood-brain barrier function of deep gray matter structures in neuroborreliosis: a case-control study.European radiology experimental · 2023Article
- Cognitive function in patients with neuroborreliosis: A prospective cohort study from the acute phase to 12 months post treatment.Brain and behavior · 2022Article
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Authors and funding
10 authors.
Funding
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Abstract
backgroundLong-term cognitive problems after neuroborreliosis treatment remain a subject of debate. We have previously shown that cognitive problems are not present in the acute phase of neuroborreliosis, although fatigue is common. The aim of this study was to re-assess the same patient cohort and evaluate long-term outcomes.
methodsIn this follow-up, we re-assessed 58 patients with well-characterized neuroborreliosis 12 months after completing treatment. The same protocol with eight subtests measuring attention and processing speed and the Fatigue Severity Scale (FSS) were used to compare the results from the acute phase to 12 months post treatment.
resultsWe found no changes in attention or processing speed but a reduction in the level of fatigue (median score on FSS: 4.9 vs. 3.9, p < .001) from the acute phase to 12 months post treatment.
conclusionThe patient group did not develop problems with attention or processing speed post treatment, while the level of fatigue decreased.
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