Evidence map›Paper›PMID 35593254›Full record

ReviewNucleus (Austin, Tex.)2022

Spelling out the roles of individual nucleoporins in nuclear export of mRNA.

Mark Tingey, Yichen Li, Wenlan Yu, Albert Young, Weidong Yang

Open access · goldAbstract readReview
In one paragraph

Review in Nucleus (Austin, Tex.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Mark TingeyDepartment of Biology, Temple University, Philadelphia, Pennsylvania, USA.
Yichen LiDepartment of Genetics, Yale School of Medicine, Yale University, New Haven, Connecticut, USA.
Wenlan YuDepartment of Biology, Temple University, Philadelphia, Pennsylvania, USA.
Albert YoungDepartment of Biology, Temple University, Philadelphia, Pennsylvania, USA.
Weidong YangDepartment of Biology, Temple University, Philadelphia, Pennsylvania, USA.
Temple University · USYale University · US

Funding

Super-resolution Microscopy Study of Molecular Transport MechanismsR35GM122552 · NIGMS · TEMPLE UNIV OF THE COMMONWEALTH · PI Weidong Yang · 2017 to 2026
$4.5M
Structure and Function of the Ciliary Pore ComplexR01GM116204 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI VERHEY, KRISTEN J., YANG, WEIDONG · 2015 to 2018
$2.1M
NIGMS NIH HHS R01 GM116204NIGMS NIH HHS R35 GM122552
6 · The paper itself

Abstract

The Nuclear Pore Complex (NPC) represents a critical passage through the nuclear envelope for nuclear import and export that impacts nearly every cellular process at some level. Recent technological advances in the form of Auxin Inducible Degron (AID) strategies and Single-Point Edge-Excitation sub-Diffraction (SPEED) microscopy have enabled us to provide new insight into the distinct functions and roles of nuclear basket nucleoporins (Nups) upon nuclear docking and export for mRNAs. In this paper, we provide a review of our recent findings as well as an assessment of new techniques, updated models, and future perspectives in the studies of mRNA's nuclear export.

Indexed as

Nuclear PoreNuclear Pore Complex ProteinsActive Transport, Cell NucleusRNA, MessengerRNA TransportNuclear Pore Complex ProteinsRNA, MessengermRNA biologyNucleocytoplasmic transportsuper-resolution light microscopy

Identifiers

PMID35593254
PMCPMC9132428
OpenAlexW4280572179

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.