Evidence map›Paper›PMID 35592828›Full record

ArticleAlzheimer's & dementia (Amsterdam, Netherlands)2022

Association of the top 20 Alzheimer's disease risk genes with [

Eddie Stage, Shannon L Risacher, Kathleen A Lane, Sujuan Gao, Kwangsik Nho, Andrew J Saykin, Liana G Apostolova, Alzheimer's Disease Neuroimaging Initiative

Open access · goldAbstract read
In one paragraph

Article in Alzheimer's & dementia (Amsterdam, Netherlands), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. The ABC's of Alzheimer risk gene ABCA7.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Sex and APOE ε4 carrier effects on atrophy, amyloid PET, and tau PET burden in early-onset Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023
    Article
  10. Article
  11. Association of the top 20 Alzheimer's disease risk genes with [Alzheimer's & dementia (Amsterdam, Netherlands) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Eddie StageDepartment of Neurology Indiana University School of Medicine Indianapolis Indiana USA.
Shannon L RisacherDepartment of Radiology and Imaging Sciences Indiana University School of Medicine Indianapolis Indiana USA.
Kathleen A LaneDepartment of Biostatistics Indiana University School of Medicine Indianapolis Indiana USA.
Sujuan GaoDepartment of Biostatistics Indiana University School of Medicine Indianapolis Indiana USA.
Kwangsik NhoDepartment of Radiology and Imaging Sciences Indiana University School of Medicine Indianapolis Indiana USA.
Andrew J SaykinDepartment of Neurology Indiana University School of Medicine Indianapolis Indiana USA.
Liana G ApostolovaDepartment of Neurology Indiana University School of Medicine Indianapolis Indiana USA.
Alzheimer's Disease Neuroimaging Initiative
Indiana University – Purdue University Indianapolis · USIndiana University School of Medicine

Funding

Alzheimer's Disease Neuroimaging Initiative - SupplementU01AG024904 · NIA · NORTHERN CALIFORNIA INSTITUTE RES &EDUC · PI WEINER, MICHAEL W · 2004 to 2015
$121.0M
Early Onset AD Consortium - the LEAD Study (LEADS)U01AG057195 · NIA · INDIANA UNIVERSITY INDIANAPOLIS · PI APOSTOLOVA, LIANA G, CARRILLO, MARIA C · 2018 to 2023
$70.3M
Research Education ComponentP30AG010133 · NIA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI GHETTI, BERNARDINO FRANCESCO · 1991 to 2020
$37.3M
Research Education ComponentP30AG072976 · NIA · INDIANA UNIVERSITY INDIANAPOLIS · PI ANDREW J SAYKIN · 2021 to 2026
$24.1M
Ultrascale Machine Learning to Empower Discovery in Alzheimers Disease BiobanksU01AG068057 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Christos Davatzikos, Heng Huang · 2020 to 2026
$20.7M
Early Onset Alzheimer's Disease ConsortiumR56AG057195 · NIA · INDIANA UNIVERSITY INDIANAPOLIS · PI APOSTOLOVA, LIANA G, CARRILLO, MARIA C · 2017 to 2017
$7.7M
Memory Circuitry in MCI and Early Alzheimer’s Disease Prodrome: Molecular DriversR01AG019771 · NIA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI SAYKIN, ANDREW J · 2001 to 2021
$6.9M
Multi-Domain Sensory Measures as Biomarkers of Alzheimer's Disease in Preclinical and Prodromal StagesR01AG061788 · NIA · INDIANA UNIVERSITY INDIANAPOLIS · PI RISACHER, SHANNON L · 2019 to 2023
$3.0M
Imaging and genetic biomarkers for Alzheimer's diseaseR01AG040770 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI APOSTOLOVA, LIANA G · 2012 to 2016
$1.4M
Informatics Algorithms for Genomic Analysis of Brain Imaging DataR01LM013463 · NLM · UNIVERSITY OF PENNSYLVANIA · PI MOORE, JASON H., SAYKIN, ANDREW J · 2020 to 2023
$1.4M
Sensory and Perceptual Measures as Biomarkers of Alzheimer's Disease PathologyK01AG049050 · NIA · INDIANA UNIVERSITY INDIANAPOLIS · PI RISACHER, SHANNON L · 2015 to 2019
$612k
Imaging epigenetics of Alzheimer's DiseaseK02AG048240 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI APOSTOLOVA, LIANA G · 2014 to 2016
$434k
NIA NIH HHS K01 AG049050NIA NIH HHS K02 AG048240NIA NIH HHS P30 AG010133NIA NIH HHS P30 AG072976NIA NIH HHS R01 AG019771NIA NIH HHS R01 AG040770NIA NIH HHS R01 AG061788NIA NIH HHS R56 AG057195NIA NIH HHS U01 AG024904NIA NIH HHS U01 AG057195NIA NIH HHS U01 AG068057NLM NIH HHS R01 LM013463
6 · The paper itself

Abstract

Introduction: We previously reported genetic associations of the top Alzheimer's disease (AD) risk alleles with amyloid deposition and neurodegeneration. Here, we report the association of these variants with [ Methods: We analyzed the [ Results: Discussion: We found significant associations to tau deposition for

Indexed as

Alzheimer's diseaseAlzheimer's Disease Neuroimaging Initiativeflortaucipirimaging geneticsrisk genes

Identifiers

PMID35592828
PMCPMC9092485
OpenAlexW4285243640

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.