Evidence map›Paper›PMID 35592685›Full record

ArticleComputational and mathematical methods in medicine2022

High-Concentration Metformin Reduces Oxidative Stress Injury and Inhibits the Growth and Migration of Clear Cell Renal Cell Carcinoma.

Yang Liu, Jianwei Li, Miaomiao Song, Guisong Qi, Lingling Meng

Open access · hybridAbstract read
In one paragraph

Article in Computational and mathematical methods in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Observational
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yang LiuThe Second Department of Urology, Cangzhou Central Hospital, China.
Jianwei LiThe Second Department of Urology, Cangzhou Central Hospital, China.
Miaomiao SongThe Second Department of Urology, Cangzhou Central Hospital, China.
Guisong QiThe Second Department of Urology, Cangzhou Central Hospital, China.
Lingling MengThe Third Department of Endocrinology, Central Hospital of Cangzhou, China.ORCID https://orcid.org/0000-0001-5576-5842
Cangzhou Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To explore the mechanism of metformin in treating Methods: Prospective cohort study was conducted. Results: In the edge tissue, Conclusion: High-concentration metformin can reduce oxidative stress injury, increase the expression of

Indexed as

Carcinoma, Renal CellKidney NeoplasmsMetforminCell Line, TumorCell MovementCell ProliferationCyclin DHumansOxidative StressProspective StudiesSuperoxide DismutaseCyclin DMetforminSuperoxide Dismutase

Identifiers

PMID35592685
PMCPMC9113878
OpenAlexW4280642422

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.