Evidence map›Paper›PMID 35592551›Full record

ArticlePharmacogenomics and personalized medicine2022

Psoriasis Patients with Specific HLA-Cw Alleles and Lower Plasma IL-17 Level Show Improved Response to Topical Lindioil Treatment.

Yin-Ku Lin, Ching-Ya Wang, Yu-Huei Huang, Ya-Ching Chang, Chun-Bing Chen, Chuang-Wei Wang, Rosaline Chung-Yee Hui, Wen-Hung Chung

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmacogenomics and personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

Yin-Ku LinDepartment of Traditional Chinese Medicine, Chang Gung Memorial Hospital, Keelung, Taiwan.
Ching-Ya WangChang Gung Memorial Hospital, Linkou Branch, Taoyuan, Taiwan.ORCID 0000-0003-1118-0900
Yu-Huei HuangChang Gung Memorial Hospital, Linkou Branch, Taoyuan, Taiwan.
Ya-Ching ChangChang Gung Memorial Hospital, Linkou Branch, Taoyuan, Taiwan.ORCID 0000-0003-4937-7557
Chun-Bing ChenChang Gung Memorial Hospital, Linkou Branch, Taoyuan, Taiwan.ORCID 0000-0002-7378-4235
Chuang-Wei Wang *Chang Gung Memorial Hospital, Linkou Branch, Taoyuan, Taiwan.ORCID 0000-0002-7921-4129
Rosaline Chung-Yee Hui *Chang Gung Memorial Hospital, Linkou Branch, Taoyuan, Taiwan.
Wen-Hung Chung *Chang Gung Memorial Hospital, Linkou Branch, Taoyuan, Taiwan.ORCID 0000-0003-1681-0959
Chang Gung University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Lindioil, a medicine refined from indigo naturalis (a herb used in Chinese medicine), is effective in treating severe psoriasis; however, responses vary across individual patients. We aim to investigate genetic predispositions associated with treatment response to topical Lindioil among patients with psoriasis and correlations with plasma cytokine patterns. Patients and Methods: We enrolled 72 psoriasis patients treated with Lindioil ointment and analyzed the human leukocyte antigen class C ( Results: Patients harboring Conclusion: Our findings suggest that the presence of the

Indexed as

HLA-Cw*01:02HLA-Cw*06:02IL-17indigo naturalisLindioilpsoriasis

Identifiers

PMID35592551
PMCPMC9113440
OpenAlexW4280561362

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.