Evidence map›Paper›PMID 35592511›Full record

ArticleJournal of the Endocrine Society2022

Tina Schubert, Nicole Reisch, Ronald Naumann, Ilka Reichardt, Dana Landgraf, Friederike Quitter, Shamini Ramkumar Thirumalasetty, Anne-Kristin Heninger, Mihail Sarov, Mirko Peitzsch and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the Endocrine Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. A Humanized and Viable Animal Model for Congenital Adrenal Hyperplasia-International journal of molecular sciences · 2024
    Article
  2. Article
  3. Models of Congenital Adrenal Hyperplasia for Gene Therapies Testing.International journal of molecular sciences · 2023
    Review
  4. Journal of the Endocrine Society · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Tina SchubertChildren's Hospital, Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, 01307 Dresden, Germany.ORCID https://orcid.org/0000-0002-4845-5376
Nicole ReischMedizinische Klinik und Poliklinik IV, Ludwig-Maximilians-Universität München, 80336 Munich, Germany.ORCID https://orcid.org/0000-0002-7469-6069
Ronald NaumannTransgenic Core Facility, Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.ORCID https://orcid.org/0000-0003-2084-5150
Ilka ReichardtGenome Engineering Facility, Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.ORCID https://orcid.org/0000-0001-7964-9352
Dana LandgrafChildren's Hospital, Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, 01307 Dresden, Germany.ORCID https://orcid.org/0000-0001-6794-1305
Friederike QuitterChildren's Hospital, Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, 01307 Dresden, Germany.ORCID https://orcid.org/0000-0002-7352-5866
Shamini Ramkumar ThirumalasettyChildren's Hospital, Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, 01307 Dresden, Germany.ORCID https://orcid.org/0000-0002-7360-7941
Anne-Kristin HeningerGenome Engineering Facility, Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.ORCID https://orcid.org/0000-0003-3151-826X
Mihail SarovGenome Engineering Facility, Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.ORCID https://orcid.org/0000-0003-2895-4087
Mirko PeitzschInstitute of Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus, Technische Universität Dresden, 01307 Dresden, Germany.ORCID https://orcid.org/0000-0002-2472-675X
Angela HuebnerChildren's Hospital, Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, 01307 Dresden, Germany.ORCID https://orcid.org/0000-0003-1338-5192
Katrin KoehlerChildren's Hospital, Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, 01307 Dresden, Germany.ORCID https://orcid.org/0000-0002-9407-1410
University Hospital Carl Gustav Carus · DEMax Planck Institute of Molecular Cell Biology and Genetics · DELudwig-Maximilians-Universität München · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Steroid 21-hydroxylase is an enzyme of the steroid pathway that is involved in the biosynthesis of cortisol and aldosterone by hydroxylation of 17α-hydroxyprogesterone and progesterone at the C21 position. Mutations in

Indexed as

21-hydroxylaseCAHcongenital adrenal hyperplasiaCyp21a1CYP21A2humanized mouse model

Identifiers

PMID35592511
PMCPMC9113096
OpenAlexW4223446953

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.