Evidence map›Paper›PMID 35592415›Full record

SynthesisFrontiers in pharmacology2022

Phytotherapy for Attention Deficit Hyperactivity Disorder (ADHD): A Systematic Review and Meta-analysis.

Tusheema Dutta, Uttpal Anand, Shreya Sikdar Mitra, Mimosa Ghorai, Niraj Kumar Jha, Nusratbanu K Shaikh, Mahipal S Shekhawat, Devendra Kumar Pandey, Jarosław Proćków, Abhijit Dey

Erratum issuedOpen access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

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  9. Frontiers in pharmacology · 2022
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

Tusheema DuttaDepartment of Life Sciences, Presidency University, Kolkata, India.
Uttpal AnandCytoGene Research & Development LLP, Lucknow, Uttar Pradesh, India.
Shreya Sikdar MitraDepartment of Life Sciences, Presidency University, Kolkata, India.
Mimosa GhoraiDepartment of Life Sciences, Presidency University, Kolkata, India.
Niraj Kumar JhaDepartment of Biotechnology, School of Engineering & Technology, Sharda University, Greater Noida, India.
Nusratbanu K ShaikhDepartment of Pharmaceutical Chemistry, Smt N. M. Padalia Pharmacy College, Ahmedabad, India.
Mahipal S ShekhawatDepartment of Plant Biology and Biotechnology, Kanchi Mamunivar Government Institute for Postgraduate Studies and Research, Lawspet, India.
Devendra Kumar PandeyDepartment of Biotechnology, School of Biosciences, Lovely Professional University, Phagwara, India.
Jarosław ProćkówDepartment of Plant Biology, Institute of Environmental Biology, Wrocław University of Environmental and Life Sciences, Wrocław, Poland.
Abhijit DeyDepartment of Life Sciences, Presidency University, Kolkata, India.
Presidency University · INBen-Gurion University of the Negev · ILKanchi Mamunivar Centre for Post Graduate Studies · INLovely Professional University · INSharda University · INWroclaw University of Environmental and Life Sciences · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Attention deficit hyperactivity disorder (ADHD) is commonly a neurodevelopmental behavioural disorder in children and adolescents. Mainly characterized by symptoms like lack of attention, hyperactivity, and impulsiveness, it can impact the overall mental development of the one affected. Several factors, both genetic and non-genetic, can be responsible for this disorder. Although several traditional treatment methods involve medication and other counselling techniques, they also come with different side effects. Hence, the choice is now shifting to alternative treatment techniques. Herbal treatments are considered one of the most popular complementary and alternative medicine (CAM) administered. However, issues related to the safety and efficacy of herbal remedies for the treatment of ADHD need to be investigated further. This study aims to find out the recent advancement in evidence-based use of herbal remedies for ADHD by a comprehensive and systematic review that depicts the results of the published works on herbal therapy for the disorder. The electronic databases and the references retrieved from the included studies present related randomized controlled trials (RCTs) and open-label studies. Seven RCTs involving children and adolescents diagnosed with ADHD met the inclusion criteria. There is a fair indication of the efficacy and safety of Melissa officinalis L., Bacopa monnieri (L.) Wettst., Matricaria chamomilla L., and Valeriana officinalis L. from the studies evaluated in this systematic review for the treatment of various symptoms of ADHD. Limited evidence was found for Ginkgo biloba L. and pine bark extract. However, various other preparations from other plants did not show significant efficacy. There is inadequate proof to strongly support and recommend the administration of herbal medicines for ADHD, but more research is needed in the relevant field to popularize the alternative treatment approach.

Indexed as

attention deficit hyperactivity disorder (ADHD)complementary alternative medicine (CAM)herbal treatmentsMelissa officinalis L.phytotherapyValeriana officinalis L

Identifiers

PMID35592415
PMCPMC9110892
OpenAlexW4225368734

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.