Evidence map›Paper›PMID 35592393›Full record

SynthesisFrontiers in cardiovascular medicine2022

Stereotactic Radiotherapy Ablation and Atrial Fibrillation: Technical Issues and Clinical Expectations Derived From a Systematic Review.

Jessica Franzetti, Stefania Volpe, Valentina Catto, Edoardo Conte, Consiglia Piccolo, Matteo Pepa, Gaia Piperno, Anna Maria Camarda, Federica Cattani, Daniele Andreini and 3 more

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Linear accelerator-based stereotactic arrhythmia radioablation for paroxysmal atrial fibrillation in elderly: a prospective phase II trial.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
    Trial
  2. Article
  3. Review
  4. When radiation meets the heart: Future of stereotactic body radiation therapy for hypertrophic obstructive cardiomyopathy.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2023
    Article
  5. Article
  6. Article
  7. Non-Oncological Radiotherapy: A Review of Modern Approaches.Journal of personalized medicine · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Jessica FranzettiDepartment of Radiation Oncology, European Institute of Oncology (IEO) IRCCS, Milan, Italy.
Stefania VolpeDepartment of Radiation Oncology, European Institute of Oncology (IEO) IRCCS, Milan, Italy.
Valentina CattoDepartment of Clinical Electrophysiology and Cardiac Pacing, Centro Cardiologico Monzino IRCCS, Milan, Italy.
Edoardo ConteCardiovascular Computed Tomography and Radiology Unit, Centro Cardiologico Monzino IRCCS, Milan, Italy.
Consiglia PiccoloUnit of Medical Physics, European Institute of Oncology (IEO) IRCCS, Milan, Italy.
Matteo PepaDepartment of Radiation Oncology, European Institute of Oncology (IEO) IRCCS, Milan, Italy.
Gaia PipernoDepartment of Radiation Oncology, European Institute of Oncology (IEO) IRCCS, Milan, Italy.
Anna Maria CamardaDepartment of Radiation Oncology, European Institute of Oncology (IEO) IRCCS, Milan, Italy.
Federica CattaniUnit of Medical Physics, European Institute of Oncology (IEO) IRCCS, Milan, Italy.
Daniele AndreiniCardiovascular Computed Tomography and Radiology Unit, Centro Cardiologico Monzino IRCCS, Milan, Italy.
Claudio TondoDepartment of Clinical Electrophysiology and Cardiac Pacing, Centro Cardiologico Monzino IRCCS, Milan, Italy.
Barbara Alicja Jereczek-FossaDepartment of Radiation Oncology, European Institute of Oncology (IEO) IRCCS, Milan, Italy.
Corrado CarbucicchioDepartment of Clinical Electrophysiology and Cardiac Pacing, Centro Cardiologico Monzino IRCCS, Milan, Italy.
European Institute of Oncology · ITCentro Cardiologico Monzino · ITUniversity of Milan · ITLuigi Sacco Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: The purpose of this study is to collect available evidence on the feasibility and efficacy of stereotactic arrhythmia radio ablation (STAR), including both photon radiotherapy (XRT) and particle beam therapy (PBT), in the treatment of atrial fibrillation (AF), and to provide cardiologists and radiation oncologists with a practical overview on this topic. Methods: Three hundred and thirty-five articles were identified up to November 2021 according to preferred reporting items for systematic reviews and meta-analyses criteria; preclinical and clinical studies were included without data restrictions or language limitations. Selected works were analyzed for comparing target selection, treatment plan details, and the accelerator employed, addressing workup modalities, acute and long-term side-effects, and efficacy, defined either by the presence of scar or by the absence of AF recurrence. Results: Twenty-one works published between 2010 and 2021 were included. Seventeen studies concerned XRT, three PBT, and one involved both. Nine studies (1 Conclusion: STAR is an innovative non-invasive procedure already applied for experimental treatment of ventricular arrhythmias. Particular attention must be paid to safety, rather than efficacy of STAR, given the benign nature of AF. Uncertainties persist, mainly regarding the definition of the treatment plan and the role of the target motion. In this setting, more information about the toxicity profile of this new approach is compulsory before applying STAR to AF in clinical practice.

Indexed as

arrhythmiasatrial fibrillationparticle beam radiotherapystereotactic arrhythmia radio ablation (STAR)stereotactic body radiotherapy (SBRT)systematic reviewtarget motion

Identifiers

PMID35592393
PMCPMC9110686
OpenAlexW4225401224

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.